ID A0A1E8CG32_9GAMM Unreviewed; 644 AA.
AC A0A1E8CG32;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=DNA (cytosine-5-)-methyltransferase {ECO:0000256|ARBA:ARBA00011975};
DE EC=2.1.1.37 {ECO:0000256|ARBA:ARBA00011975};
GN ORFNames=PHACT_12775 {ECO:0000313|EMBL:OFE11424.1};
OS Pseudohongiella acticola.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudohongiellaceae; Pseudohongiella.
OX NCBI_TaxID=1524254 {ECO:0000313|EMBL:OFE11424.1, ECO:0000313|Proteomes:UP000175669};
RN [1] {ECO:0000313|Proteomes:UP000175669}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KCTC 42131 {ECO:0000313|Proteomes:UP000175669};
RA Florea S., Webb J.S., Jaromczyk J., Schardl C.L.;
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-
CC methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine;
CC Xref=Rhea:RHEA:13681, Rhea:RHEA-COMP:11369, Rhea:RHEA-COMP:11370,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:85452, ChEBI:CHEBI:85454; EC=2.1.1.37;
CC Evidence={ECO:0000256|ARBA:ARBA00000743};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OFE11424.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MASR01000002; OFE11424.1; -; Genomic_DNA.
DR RefSeq; WP_070118663.1; NZ_MASR01000002.1.
DR AlphaFoldDB; A0A1E8CG32; -.
DR STRING; 1524254.PHACT_12775; -.
DR OrthoDB; 9813719at2; -.
DR Proteomes; UP000175669; Unassembled WGS sequence.
DR GO; GO:0003886; F:DNA (cytosine-5-)-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009307; P:DNA restriction-modification system; IEA:UniProtKB-KW.
DR Gene3D; 3.90.120.10; DNA Methylase, subunit A, domain 2; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR001525; C5_MeTfrase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR10629; CYTOSINE-SPECIFIC METHYLTRANSFERASE; 1.
DR PANTHER; PTHR10629:SF50; DNA (CYTOSINE-5)-METHYLTRANSFERASE CMT3; 1.
DR Pfam; PF00145; DNA_methylase; 3.
DR PRINTS; PR00105; C5METTRFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000175669};
KW Restriction system {ECO:0000256|ARBA:ARBA00022747};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
SQ SEQUENCE 644 AA; 70066 MW; 1DEAA7580349C1D2 CRC64;
MTGMEFKTQY GLSFDGKINV DLFAGGGGAS TGIEMGTNRP VHIAINHDPD AISMHQANHP
AAKHFVSDVY DVDPVEACEG RPVGHLHASP DCTHHSQASG GQPRKAAIRS LSWVVHRWAG
KVRPDVITLE NVAQILQWSP LVAKRCSKTG RVVTLDTVKC AKTGRMVSRV AGKGEQVPVD
RQHLVPNKRK RGHNWQHFVG GLRAMGYQVE WRSLKACEYG APTTRERLYL VARCDGKPIV
WPAPTHAQKP KRGQKKWRTA ADCIDWSIPG KSIFGRKRPL ADATMRRIAK GVKKYVLDTA
EPFIVTCNHG GERFRGQSIH EPMCTITAAH DAHGVVDATL APFLTEHANS SNQRSMAADE
PLRTITGYPK GGSFAMASAV MAPCIMVNQT NNEGGPVTAP VTTITTGQHH AVTTAYLAQM
NGGFNTNPGH DARDPISTIT NTGSQQQLVT AHLAHLRGNC DARAADEPVR TISAGGEHHG
MVTAFLSRQF GASVGQGVDQ PSPTATGREK TALIECQLSP EDEAGAMRVS GFLMQYYSEG
GQWSGLDKPT NTITTKERLA LVTVYLQGAP YVIVDIRLRM LTPRELFRAQ GFPDSYIIDR
GHDGRVFPKY KQVRFVGNSV SPLPMKALSR ANLDPEPVRM EAAA
//
