ID   A0A1E8CZZ6_9MICO        Unreviewed;      1437 AA.
AC   A0A1E8CZZ6;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Cell division protein FtsK {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BA895_12800 {ECO:0000313|EMBL:OFE18023.1};
OS   Humibacillus sp. DSM 29435.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Intrasporangiaceae;
OC   Humibacillus.
OX   NCBI_TaxID=1869167 {ECO:0000313|EMBL:OFE18023.1, ECO:0000313|Proteomes:UP000175826};
RN   [1] {ECO:0000313|Proteomes:UP000175826}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 29435 {ECO:0000313|Proteomes:UP000175826};
RA   Florea S., Webb J.S., Jaromczyk J., Schardl C.L.;
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OFE18023.1}.
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DR   EMBL; MAST01000003; OFE18023.1; -; Genomic_DNA.
DR   RefSeq; WP_070190469.1; NZ_MAST01000003.1.
DR   STRING; 1869167.BA895_12800; -.
DR   OrthoDB; 9807790at2; -.
DR   Proteomes; UP000175826; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   CDD; cd00060; FHA; 1.
DR   CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR   Gene3D; 2.60.200.20; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR000253; FHA_dom.
DR   InterPro; IPR002543; FtsK_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR008984; SMAD_FHA_dom_sf.
DR   InterPro; IPR032030; YscD_cytoplasmic_dom.
DR   PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR   PANTHER; PTHR22683:SF1; TYPE VII SECRETION SYSTEM PROTEIN ESSC; 1.
DR   Pfam; PF01580; FtsK_SpoIIIE; 2.
DR   Pfam; PF16697; Yop-YscD_cpl; 1.
DR   SMART; SM00382; AAA; 3.
DR   SMART; SM00240; FHA; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR   SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR   PROSITE; PS50006; FHA_DOMAIN; 1.
DR   PROSITE; PS50901; FTSK; 2.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00289}; Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00289}; Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000175826};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        236..253
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          117..166
FT                   /note="FHA"
FT                   /evidence="ECO:0000259|PROSITE:PS50006"
FT   DOMAIN          639..831
FT                   /note="FtsK"
FT                   /evidence="ECO:0000259|PROSITE:PS50901"
FT   DOMAIN          964..1145
FT                   /note="FtsK"
FT                   /evidence="ECO:0000259|PROSITE:PS50901"
FT   BINDING         657..664
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
FT   BINDING         982..989
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ   SEQUENCE   1437 AA;  151392 MW;  D5E4A19A17F1B64E CRC64;
     MRLRLRLIDP RSNPSGHLDV LVECAPATPF GVLRGRLAEL VVDASDGFEV DGILVSDDAE
     WGAPPLLQGA ALTARASGFT SGRTPGRTPS RPVGLLELHV VGGPGAGRRV PLSRGEHVLG
     RAPHCAVRLD DAGVSRAHAT LTVGDDGVTL RDVEPTNPTM VNDRPTPPAG VPLAVGARAR
     LASTTLVLRR PTSTPAPITL DAGLLRLHRR PRFVSTASPV VVAFPARPKR SERSRMPLLA
     SLTPLVVSGA LALALHSPIM LLFALMSPVM LLGQWWSDRR HGRTSLRRQL ADHAVAVAAA
     EHQLHSVVQR EEHERRAEHP DLAEVALVAE LRDARLWQRT PGDPDDLVVR LGSADLEARA
     TVTGEPTSPT PTCHDVPVTC DLADAGVVGV AGPRERVLAV AGSMLAQLCV WHSPQRVDLV
     LLTTSASPEA DWAWLTRTPH LDGADRSVAR VGTLGDGLSI AARVSELTEQ VAMRASARAA
     HDDGKLAALP TVVVVLDGAR ELRAVAGVAE LLQSGPALDV RFICLDVSIS ALPAETVSQI
     EVHSSTEPRA TLTTRRGVVG EPAGIVPDLP TGGWLERLGS SLSPLQDATP RRGDAGLPEQ
     LGFRELAAQE GNDPAAATDL VRAWADGGRP RALVGVTREG PYWLDLAHHG PHALVGGTTG
     AGKSEMLQTL VAGLAVSSRP DDLGFVLIDY KGGSAFKECS RLPHVVGLVT DLDESLTSRA
     LTSLGAELKR RERVLAASGA KDVDDHRRRR LADASLPRLG RLVIVVDEFK MLADELPDFV
     SGLVQLAAVG RSLGVHLVLA TQRPGGIVSA DMRANVSLRV ALRVRDRSDS DDVIEDPRAA
     TISDRIPGRA FVRTADQRLV EVQFAHVGAV LEAAREAGTE AMLWPLRWSN LAEAAPTATT
     RKAGERTQLA AVVDATREAA AALSIEATPA PWLTPLPSSL PVSSLPRADG GVPIGLRDEP
     EQQSQPVLTW HPEADGHLGI AGSSRTGRST ALRSLVVGLT ERHSPAELHV HVLEGRRGAL
     TDLLALPHVG SVTSADDPVL ARRVVSHISD ATRSNVSNDR RAPRTVLVVD GWEAIEDAFS
     DLDHGAPTDE LLRLARDGLS TGLRLVVAGG RAVSTGRLSG LLQRRIVLAM PDPLDLTLAG
     VDARRASTPL PPGRGFELPG GHLVHLAHVG TSVEQPSQVA AVESAADLAH LRSHDVPPQR
     LPWRVRALPT TVAPTELQPD GQSLCIGLGG DDATTVHLDP AASGRRLLVA GPARSGRSTI
     LALIAQQLVA AGRPVAVVIG RRSRLGELAG LPGVHLLDAS ARDGFVELRR ATPELGILVD
     DAENLVGTPM EAALLEATAI VDTAEGVVVV AAETQRALGL FRGLVPEVSR DGCGILLSPA
     SAADGDLLRV RVDVPSERRP GFGFVVVDGS CTPVQVADAF ALPALAGQHP PPPTVRS
//