ID A0A1E8FEM7_9ALTE Unreviewed; 321 AA.
AC A0A1E8FEM7;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Cyclic pyranopterin phosphate synthase {ECO:0000313|EMBL:OFI34371.1};
GN Name=moaA {ECO:0000313|EMBL:OFI34371.1};
GN ORFNames=BFC17_18500 {ECO:0000313|EMBL:OFI34371.1};
OS Alteromonas lipolytica.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Alteromonadaceae; Alteromonas/Salinimonas group; Alteromonas.
OX NCBI_TaxID=1856405 {ECO:0000313|EMBL:OFI34371.1, ECO:0000313|Proteomes:UP000176037};
RN [1] {ECO:0000313|EMBL:OFI34371.1, ECO:0000313|Proteomes:UP000176037}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JW12 {ECO:0000313|EMBL:OFI34371.1,
RC ECO:0000313|Proteomes:UP000176037};
RA Wu Y.-H., Cheng H., Xu X.-W.;
RT "Alteromonas lipolytica, a new species isolated from sea water.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OFI34371.1}.
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DR EMBL; MJIC01000013; OFI34371.1; -; Genomic_DNA.
DR RefSeq; WP_070176487.1; NZ_MJIC01000013.1.
DR AlphaFoldDB; A0A1E8FEM7; -.
DR STRING; 1856405.BFC17_18500; -.
DR OrthoDB; 9763993at2; -.
DR Proteomes; UP000176037; Unassembled WGS sequence.
DR GO; GO:0019008; C:molybdopterin synthase complex; IEA:InterPro.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd21117; Twitch_MoaA; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR013483; MoaA.
DR InterPro; IPR000385; MoaA_NifB_PqqE_Fe-S-bd_CS.
DR InterPro; IPR010505; MoaA_twitch.
DR InterPro; IPR007197; rSAM.
DR NCBIfam; TIGR02666; moaA; 1.
DR PANTHER; PTHR22960:SF28; GTP 3',8-CYCLASE; 1.
DR PANTHER; PTHR22960; MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A; 1.
DR Pfam; PF06463; Mob_synth_C; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01383; cyclic_pyranopterin_phosphate; 1.
DR SFLD; SFLDG01216; thioether_bond_formation_requi; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS01305; MOAA_NIFB_PQQE; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Molybdenum cofactor biosynthesis {ECO:0000256|ARBA:ARBA00023150};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000176037};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 5..227
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 321 AA; 35148 MW; EAB291E920BC6158 CRC64;
MLQDSFGRRF YYLRLSITDV CNFRCQYCLP DGYQGEAQQF LSVNEIDTLV NAFAQMGTSK
IRITGGEPTL RRDIVDVVAR CAVTPGISKV AMTTHAGKLA SLATPLAAAG LKQVNISLDS
LEPAQFALLS GQDKLAAVLD GVESALVEGM NVKVNAVLMR PWAESQLRDF TAWLKDMPVT
VRFIELMETG QHKAFFKSHH VSAEPYLAAL RQQGWQALPR GKDAGPAIEL AHPDYVGNIG
FIMPYSSDFC NSCNRLRITA LGKLHLCLFS DQGLDLRESL QSGDVEAVKT FVTDSLADKK
VSHYLQDGIT GITRNLSMLG G
//
