ID A0A1E8FL24_9MICC Unreviewed; 289 AA.
AC A0A1E8FL24;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Rhomboid family intramembrane serine protease {ECO:0000313|EMBL:OFI36466.1};
GN ORFNames=BIU82_13255 {ECO:0000313|EMBL:OFI36466.1};
OS Arthrobacter sp. SW1.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=1920889 {ECO:0000313|EMBL:OFI36466.1, ECO:0000313|Proteomes:UP000176251};
RN [1] {ECO:0000313|EMBL:OFI36466.1, ECO:0000313|Proteomes:UP000176251}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SW1 {ECO:0000313|EMBL:OFI36466.1,
RC ECO:0000313|Proteomes:UP000176251};
RA Shaligram S.M., Kumbhare S.V., Pawar S., Dhotre D., Muddeshwar M.G.,
RA Kapley A.;
RT "Genomic insights of Arthrobacter sp. strain SW1 for secondary metabolite
RT production.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the peptidase S54 family.
CC {ECO:0000256|ARBA:ARBA00009045}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OFI36466.1}.
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DR EMBL; MJLT01000069; OFI36466.1; -; Genomic_DNA.
DR RefSeq; WP_070350975.1; NZ_MJLT01000069.1.
DR AlphaFoldDB; A0A1E8FL24; -.
DR STRING; 1920889.BIU82_13255; -.
DR OrthoDB; 9807874at2; -.
DR Proteomes; UP000176251; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd19756; Bbox2; 1.
DR Gene3D; 1.20.1540.10; Rhomboid-like; 1.
DR InterPro; IPR022764; Peptidase_S54_rhomboid_dom.
DR InterPro; IPR035952; Rhomboid-like_sf.
DR PANTHER; PTHR43731:SF26; RHOMBOID DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43731; RHOMBOID PROTEASE; 1.
DR Pfam; PF01694; Rhomboid; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF144091; Rhomboid-like; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:OFI36466.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000313|EMBL:OFI36466.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000176251};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 78..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 129..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 187..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 218..235
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 120..256
FT /note="Peptidase S54 rhomboid"
FT /evidence="ECO:0000259|Pfam:PF01694"
SQ SEQUENCE 289 AA; 30769 MW; DBF2CFA19D0806E5 CRC64;
MSFGYPAAEP SAGVPVCPRH PDRPSYVRCQ RCGRPACPEC QRAAAVGFQC VDCVNELSRS
TPAVRSVYGG TAVVDRPMAT FLLIGACVVL YVLQWIVPGD VIFQNFAFAS AFADPQYGHF
EPWRMLTAAF LHSQGFVLHI ALNMYTLWIF GQALEPLLGR TRFLAIYLLS AIGGSVGYML
LTPVFPVIPV VGASGAIFGM FGAMLVIQRH RGGDTKQLWV LIAINGAIGF MVSGIAWQAH
LGGLVTGALS AAAVAYAPRG PRRALYQAAG LAVVAVLLVL ATALRTAAI
//
