ID A0A1E8Q356_9MYCO Unreviewed; 468 AA.
AC A0A1E8Q356;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=GABA permease {ECO:0000313|EMBL:OFJ52837.1};
GN ORFNames=BEL07_15260 {ECO:0000313|EMBL:OFJ52837.1};
OS Mycobacterium grossiae.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1552759 {ECO:0000313|EMBL:OFJ52837.1, ECO:0000313|Proteomes:UP000178953};
RN [1] {ECO:0000313|EMBL:OFJ52837.1, ECO:0000313|Proteomes:UP000178953}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCH {ECO:0000313|EMBL:OFJ52837.1,
RC ECO:0000313|Proteomes:UP000178953};
RA Greninger A.L., Qin X., Jerome K., Vora S., Quinn K.;
RT "genome sequence of Mycobacterium sp. 739 SCH.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
CC {ECO:0000256|ARBA:ARBA00008583}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OFJ52837.1}.
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DR EMBL; MCHX01000033; OFJ52837.1; -; Genomic_DNA.
DR RefSeq; WP_070353966.1; NZ_MCHX01000033.1.
DR AlphaFoldDB; A0A1E8Q356; -.
DR OrthoDB; 5297508at2; -.
DR Proteomes; UP000178953; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006865; P:amino acid transport; IEA:InterPro.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR004840; Amoino_acid_permease_CS.
DR PANTHER; PTHR43495; GABA PERMEASE; 1.
DR PANTHER; PTHR43495:SF5; GAMMA-AMINOBUTYRIC ACID PERMEASE; 1.
DR Pfam; PF00324; AA_permease; 1.
DR PIRSF; PIRSF006060; AA_transporter; 1.
DR PROSITE; PS00218; AMINO_ACID_PERMEASE_1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000178953};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 53..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 93..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 205..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 247..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..356
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 362..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 401..426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 432..451
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 25..451
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
SQ SEQUENCE 468 AA; 49316 MW; 158CDB0600C85797 CRC64;
MSGQVDADPA ATPGNGLGTS LKSRHITMIS IAGVIGAGLF VGSANAIAEA GPAVLISYFL
AGLLVVLVMR MLGEMATANP DTGSFSVYSD RALGRWAGFT VGWLYWWFWV LVIPVEATAA
AAILTDLVGG AQWIWALAVT LLLTITNLVS VGNYGEFEFW FALIKVVAIV AFIGVGVAAI
LGVIPDSQVS GIHHLWEPDG FMPNGFGAVI AGLLITMFSF MGTEIVTIAA AESKNPAKGI
GRAVNSVIWR ISLFYLGSIF VVVALMPYDQ LTDGSYQSVL QAIGIPGSKL IMDLVILTAV
ASCLNSALYT ASRMLFSLGE RRDAPQAVRR VAGNGAPWVA VLASMVVGFL AVAGNYLLPE
KIFGYLLATS GAVALFVYLA IASSQFVLGR RMRADGERAP VAMWLFPYLT VVTIVGIVAI
LVLMAFDPDQ QQAIGLSALS AVVIIVAGLV VQRRHAGHAA GDRYASRS
//
