ID A0A1E8Q6J5_9MYCO Unreviewed; 741 AA.
AC A0A1E8Q6J5;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Type VII secretion protein EccCa {ECO:0000313|EMBL:OFJ54106.1};
GN ORFNames=BEL07_08620 {ECO:0000313|EMBL:OFJ54106.1};
OS Mycobacterium grossiae.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1552759 {ECO:0000313|EMBL:OFJ54106.1, ECO:0000313|Proteomes:UP000178953};
RN [1] {ECO:0000313|EMBL:OFJ54106.1, ECO:0000313|Proteomes:UP000178953}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCH {ECO:0000313|EMBL:OFJ54106.1,
RC ECO:0000313|Proteomes:UP000178953};
RA Greninger A.L., Qin X., Jerome K., Vora S., Quinn K.;
RT "genome sequence of Mycobacterium sp. 739 SCH.";
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OFJ54106.1}.
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DR EMBL; MCHX01000016; OFJ54106.1; -; Genomic_DNA.
DR RefSeq; WP_070352675.1; NZ_MCHX01000016.1.
DR AlphaFoldDB; A0A1E8Q6J5; -.
DR OrthoDB; 9807790at2; -.
DR Proteomes; UP000178953; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR023836; EccCa-like_Actinobacteria.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR03924; T7SS_EccC_a; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR PANTHER; PTHR22683:SF1; TYPE VII SECRETION SYSTEM PROTEIN ESSC; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Reference proteome {ECO:0000313|Proteomes:UP000178953};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 44..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 453..663
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT BINDING 477..484
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 741 AA; 80523 MW; 33F8114C22F2D2F8 CRC64;
MTTKKFTPTI KRGPRLTPGE ITVTPPEDLG IEIPPSGMQK AMPWVMGGCM LGMIVIMIFT
GVRQLSPYML MMPLMMVMAT VGFMAGGGPG GKKVPEINAD RKEYLRYLAG LRTRVTSSAA
AQVTFFNYHA PHPDDLLSII GTHRQWSRQS NSDFYAAVRI GLGSEPAVDR LLKPAVGGEL
AGPQAAPQPH LEPVSHMWVT KFLRTHGLIH DCPKLVQLRT FPTIAVGGDG DREGLLTAMI
CHLAVFHPPD LLQIRVLTDD PEDPRWSWVK WLPHVQHQSD TDAAGATRLV FTRPDGLSDL
TARGPHTADS APAGPYVVVI DLTGGKAGFP VDGRAGVTVI TLGNHRGSAY RIRVDPDGTA
DDRLPNQSFR LVASQCDTMT AGQAGRVARK LAGWSITGTI IDKSTRVQKK VATEWHELVG
AQTIEEVTPN RWRMFTDTDR DRLKIPFGHE LKTGDIQYLD IKEGAEFGAG PHGMLIGTTG
SGKSEFLRTL ILSLVATHHP DQVNLLLTDF KGGSTFLGME RLPHTAAVVT NMEEEAELVS
RMGEVLSGEL DRRQSILRQA GMQVGAAGAL SGVAEYEKHR ERGADLPPLP TLFVVVDEFA
ELLQNHPDFI ALFDRICRVG RSLRVHLLLA TQSLNTGGVR IDKLEPNLTY RIALRTTSSA
ESKAVIGTPE AQYITNKESG VGFLRVGMED PVKFKSMYTG EPYVPAATQS ADGDSAPRHA
VASRVSIRPF TAAAIPEAVA P
//
