ID A0A1E8YKA1_9LACT Unreviewed; 535 AA.
AC A0A1E8YKA1;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 03-MAY-2023, entry version 16.
DE SubName: Full=Beta-xylosidase {ECO:0000313|EMBL:OFK56514.1};
GN ORFNames=HMPREF2811_01810 {ECO:0000313|EMBL:OFK56514.1};
OS Globicatella sp. HMSC072A10.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Aerococcaceae; Globicatella.
OX NCBI_TaxID=1739315 {ECO:0000313|EMBL:OFK56514.1, ECO:0000313|Proteomes:UP000176615};
RN [1] {ECO:0000313|EMBL:OFK56514.1, ECO:0000313|Proteomes:UP000176615}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HMSC072A10 {ECO:0000313|EMBL:OFK56514.1,
RC ECO:0000313|Proteomes:UP000176615};
RA Wen L., He K., Yang H.;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 43 family.
CC {ECO:0000256|ARBA:ARBA00009865, ECO:0000256|RuleBase:RU361187}.
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DR EMBL; KV805633; OFK56514.1; -; Genomic_DNA.
DR RefSeq; WP_071407852.1; NZ_KV805633.1.
DR AlphaFoldDB; A0A1E8YKA1; -.
DR OrthoDB; 9801455at2; -.
DR Proteomes; UP000176615; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd09000; GH43_SXA-like; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR041542; GH43_C2.
DR InterPro; IPR006710; Glyco_hydro_43.
DR InterPro; IPR023296; Glyco_hydro_beta-prop_sf.
DR PANTHER; PTHR42812; BETA-XYLOSIDASE; 1.
DR PANTHER; PTHR42812:SF12; BETA-XYLOSIDASE-RELATED; 1.
DR Pfam; PF17851; GH43_C2; 1.
DR Pfam; PF04616; Glyco_hydro_43; 1.
DR SUPFAM; SSF75005; Arabinanase/levansucrase/invertase; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361187};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361187};
KW Reference proteome {ECO:0000313|Proteomes:UP000176615}.
FT DOMAIN 331..532
FT /note="Beta-xylosidase C-terminal Concanavalin A-like"
FT /evidence="ECO:0000259|Pfam:PF17851"
FT ACT_SITE 14
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT ACT_SITE 187
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT SITE 128
FT /note="Important for catalytic activity, responsible for
FT pKa modulation of the active site Glu and correct
FT orientation of both the proton donor and substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-2"
SQ SEQUENCE 535 AA; 61630 MW; D58F0F418E33D7B1 CRC64;
MKIINPILKG FNPDPSICRV GEDYYIATST FEWFPGVQIH HSKDLKNWQL IKHPVERESQ
INMRGNSDSG GVWAPALSYS DGKFWLIYSD VKVVEGDVFK DVNNYLITCD TIDGEWSDPI
YLNSSGFDPS LFHDEDGKKY LVNMVWDYRS YNHRFYGISL QEYDHKKQKL IGDSKIIFKG
TEWGLTEAPH LYKINGYYYL LTAEGGTKYE HAATIARSET IDGPYEVHPN NPLISSALHP
FNPLQKAGHA SIVKTHTDEW FLVHLTGRPI NKASTRVSEF RGYCPLGRET AIQRLYWEND
WPYVEGGNYP SLEINGPKIK EVKWKDNYLE KDDFEDSTLN IHFNTLRIPF NEEMGSLTER
PGYLRLYGGG SPHNLFQQSM VARRWQSLKF RAETYVEFSP KTYQQFAGLV NYYSIKNWTS
IHVTMNEEKG RILDILSCDQ FKLKNELEGK EIEIPTSLSG VYLAVDVDGL SYNYSYSFDG
INWNKIEIQF ESIKLSDDYV ESGGFFTGAF VGVHAVDLTG QKLHADFDYF SYVEE
//
