ID A0A1F0G686_9PORP Unreviewed; 510 AA.
AC A0A1F0G686;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=ATP-dependent DNA helicase RecQ {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF3027_01925 {ECO:0000313|EMBL:OFO56341.1};
OS Porphyromonas sp. HMSC077F02.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Porphyromonadaceae;
OC Porphyromonas.
OX NCBI_TaxID=1739529 {ECO:0000313|EMBL:OFO56341.1, ECO:0000313|Proteomes:UP000178655};
RN [1] {ECO:0000313|Proteomes:UP000178655}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HMSC077F02 {ECO:0000313|Proteomes:UP000178655};
RA Mitreva M., Pepin K.H., Mihindukulasuriya K.A., Fulton R., Fronick C.,
RA O'Laughlin M., Miner T., Herter B., Rosa B.A., Cordes M., Tomlinson C.,
RA Wollam A., Palsikar V.B., Mardis E.R., Wilson R.K.;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OFO56341.1}.
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DR EMBL; LTSX01000057; OFO56341.1; -; Genomic_DNA.
DR RefSeq; WP_070706604.1; NZ_KV820636.1.
DR AlphaFoldDB; A0A1F0G686; -.
DR STRING; 1739529.HMPREF3027_01925; -.
DR Proteomes; UP000178655; Unassembled WGS sequence.
DR GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR CDD; cd18794; SF2_C_RecQ; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR018982; RQC_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR Pfam; PF09382; RQC; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00956; RQC; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000178655}.
FT DOMAIN 22..190
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 214..360
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 510 AA; 57465 MW; BEED2499D749F620 CRC64;
MEAALKRYFG YDHFRAHQAE VVGNVIQGFD QLVVLPTGGG KSLCYQLPAM MMEGCALVIS
PLIALMKDQV LALQERGIAA ATINSSVTQE YRNSVSMALS RGQLKLLYMS PETLMSASGM
SLVKQAKISL VAVDEAHCIS QWGHDFRPEY AQLGVLKELF PETPIIALTA TADPATQKDI
LLQLHLREPI VTIGDFDRPN IYLEIRRGLK KQEKLREILM FIEGREAHAS GIIYCTKRDD
TEMLSRYLND KGFKALYYHA QMGAGERDMV HRLFLMGQVD IVCATVAFGM GIDKPDVRWV
IHYNMPKNIE SYYQEIGRAG RDGKRADALL FYSYADIFVL QRMIQDTPMQ DLNRSKMEYM
KRYCEGNICR RKVLLSYFGA EAEDHCGKCD VCLMPKRQTM DGTVIAQKAM SAVVRTGAQV
GVEMLIDILR GSQKRLLLTM GYHTLPTYGV GRDLSALAWR EYIYQMIMLG LMKIDYADGG
KLQVTASGQE VLFGRASLAL QPFRPLPKRR
//
