ID A0A1F1EFC9_9PORP Unreviewed; 388 AA.
AC A0A1F1EFC9;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=galactokinase {ECO:0000256|ARBA:ARBA00012315};
DE EC=2.7.1.6 {ECO:0000256|ARBA:ARBA00012315};
DE AltName: Full=Galactose kinase {ECO:0000256|ARBA:ARBA00029590};
GN ORFNames=HMPREF2890_00775 {ECO:0000313|EMBL:OFR41110.1};
OS Porphyromonas sp. HMSC065F10.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Porphyromonadaceae;
OC Porphyromonas.
OX NCBI_TaxID=1739394 {ECO:0000313|EMBL:OFR41110.1, ECO:0000313|Proteomes:UP000177035};
RN [1] {ECO:0000313|EMBL:OFR41110.1, ECO:0000313|Proteomes:UP000177035}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HMSC065F10 {ECO:0000313|EMBL:OFR41110.1,
RC ECO:0000313|Proteomes:UP000177035};
RA Wen L., He K., Yang H.;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Carbohydrate metabolism; galactose metabolism.
CC {ECO:0000256|ARBA:ARBA00004947}.
CC -!- SIMILARITY: Belongs to the GHMP kinase family. GalK subfamily.
CC {ECO:0000256|ARBA:ARBA00006566}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OFR41110.1}.
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DR EMBL; LTXH01000038; OFR41110.1; -; Genomic_DNA.
DR RefSeq; WP_070464052.1; NZ_KV793738.1.
DR AlphaFoldDB; A0A1F1EFC9; -.
DR STRING; 1739394.HMPREF2890_00775; -.
DR Proteomes; UP000177035; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004335; F:galactokinase activity; IEA:InterPro.
DR GO; GO:0006012; P:galactose metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.890; GHMP kinase, C-terminal domain; 1.
DR InterPro; IPR000705; Galactokinase.
DR InterPro; IPR019741; Galactokinase_CS.
DR InterPro; IPR019539; GalKase_N.
DR InterPro; IPR013750; GHMP_kinase_C_dom.
DR InterPro; IPR036554; GHMP_kinase_C_sf.
DR InterPro; IPR006204; GHMP_kinase_N_dom.
DR InterPro; IPR006203; GHMP_knse_ATP-bd_CS.
DR InterPro; IPR006206; Mevalonate/galactokinase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR NCBIfam; TIGR00131; gal_kin; 1.
DR PANTHER; PTHR10457:SF35; GALACTOKINASE; 1.
DR PANTHER; PTHR10457; MEVALONATE KINASE/GALACTOKINASE; 1.
DR Pfam; PF10509; GalKase_gal_bdg; 1.
DR Pfam; PF08544; GHMP_kinases_C; 1.
DR Pfam; PF00288; GHMP_kinases_N; 1.
DR PIRSF; PIRSF000530; Galactokinase; 1.
DR PRINTS; PR00473; GALCTOKINASE.
DR PRINTS; PR00959; MEVGALKINASE.
DR SUPFAM; SSF55060; GHMP Kinase, C-terminal domain; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS00106; GALACTOKINASE; 1.
DR PROSITE; PS00627; GHMP_KINASES_ATP; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Galactose metabolism {ECO:0000256|ARBA:ARBA00023144};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:OFR41110.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000177035};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 12..59
FT /note="Galactokinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10509"
FT DOMAIN 116..181
FT /note="GHMP kinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00288"
FT DOMAIN 287..352
FT /note="GHMP kinase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08544"
SQ SEQUENCE 388 AA; 43129 MW; 75B772608C564331 CRC64;
MRNREIVRAA LEQTFGHTDG VSLYFAPGRI NVIGEHTDYN GGFVFPGAVD TGIMAAIRPN
GTDRINAYAI DLDERASFGL TEEDAPEEQW ARYIFGLSRE MQKLGVPVRG FDTAFSGDVP
LGAGMSSSAA LESCYARALN ELFGDSKVGD FDLAIAGQMT EHHYVGVNCG IMDQFASVFG
KEGHIMRLDC RSLEYEYFPW EPEGYRLVLI DTVVKHNLAS GAYNQRRASC EHVVKALREA
YPDRKIEYLR DADLHMLDSI RDKVSAEDAL RAEYVIEEID RVLVVSDALK AGDYPTVGRK
MYQTHWGLSM KYEVSCEELD FLVLEALHSG VTGSRVMGGG FGGCTINLVR EELYDSFIAH
ATKAYEEKFG HAPKVYPVII GDGARRLE
//
