ID A0A1F1L0Y8_9CORY Unreviewed; 517 AA.
AC A0A1F1L0Y8;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Catalase {ECO:0000313|EMBL:OFS21410.1};
GN ORFNames=HMPREF3067_06290 {ECO:0000313|EMBL:OFS21410.1};
OS Corynebacterium sp. HMSC04H06.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=1581050 {ECO:0000313|EMBL:OFS21410.1, ECO:0000313|Proteomes:UP000177657};
RN [1] {ECO:0000313|EMBL:OFS21410.1, ECO:0000313|Proteomes:UP000177657}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HMSC04H06 {ECO:0000313|EMBL:OFS21410.1,
RC ECO:0000313|Proteomes:UP000177657};
RA Ploux O.;
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|PIRSR:PIRSR038928-2};
CC -!- SIMILARITY: Belongs to the catalase family.
CC {ECO:0000256|ARBA:ARBA00005329}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OFS21410.1}.
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DR EMBL; LWPR01000045; OFS21410.1; -; Genomic_DNA.
DR RefSeq; WP_070768876.1; NZ_KV823429.1.
DR AlphaFoldDB; A0A1F1L0Y8; -.
DR STRING; 1581050.HMPREF3067_06290; -.
DR OrthoDB; 3169619at2; -.
DR Proteomes; UP000177657; Unassembled WGS sequence.
DR GO; GO:0004096; F:catalase activity; IEA:InterPro.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR Gene3D; 2.40.180.10; Catalase core domain; 1.
DR InterPro; IPR018028; Catalase.
DR InterPro; IPR024711; Catalase_clade1/3.
DR InterPro; IPR011614; Catalase_core.
DR InterPro; IPR010582; Catalase_immune_responsive.
DR InterPro; IPR020835; Catalase_sf.
DR PANTHER; PTHR11465; CATALASE; 1.
DR PANTHER; PTHR11465:SF9; CATALASE; 1.
DR Pfam; PF00199; Catalase; 1.
DR Pfam; PF06628; Catalase-rel; 1.
DR PIRSF; PIRSF038928; Catalase_clade1-3; 1.
DR PRINTS; PR00067; CATALASE.
DR SMART; SM01060; Catalase; 1.
DR SUPFAM; SSF56634; Heme-dependent catalase-like; 1.
DR PROSITE; PS51402; CATALASE_3; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|PIRSR:PIRSR038928-2};
KW Hydrogen peroxide {ECO:0000256|ARBA:ARBA00023324};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR038928-2};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR038928-2};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Peroxidase {ECO:0000256|ARBA:ARBA00022559};
KW Reference proteome {ECO:0000313|Proteomes:UP000177657}.
FT DOMAIN 25..410
FT /note="Catalase core"
FT /evidence="ECO:0000259|SMART:SM01060"
FT REGION 1..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..45
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 72
FT /evidence="ECO:0000256|PIRSR:PIRSR038928-1"
FT ACT_SITE 144
FT /evidence="ECO:0000256|PIRSR:PIRSR038928-1"
FT BINDING 354
FT /ligand="heme"
FT /ligand_id="ChEBI:CHEBI:30413"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT /evidence="ECO:0000256|PIRSR:PIRSR038928-2"
SQ SEQUENCE 517 AA; 58935 MW; DE0FB6BB82EA7E63 CRC64;
MTQDSSAADQ ILGRGNRAAG EGQTTRPSGQ PVASENRSVT AGPQGPNVLN DVHLIEKLAH
FNRERVPERT PHAKGHGAFG ELHITEDVSQ YTKAKLFQKG AVTPMAIRFS TVAGEQGSPD
TWRDVHGFAM RFYTEDGNYD IVGNNTPTFF IRDAIKFPDF IHSQKRLGTN GLRNADMQWD
FWTRSPESAH QVTYLMGDRG TPKTSRHQDG FGSHTFQWIN EEGKPVWIKY HFKTRQGWDC
FTDAEAAEMA GQNADHHRED LYNAIERGDY PVWDVKVQIM PFEDAENYRF NPFDLTKTWS
QKDYPLHDVG YFVLNRNPRN FFAQIEQLAL DPANLVPGVG LSPDRMLQGR VFAYSDQQRY
RIGPNYKQLP VNQPLNADKV NTYEHEGPMS FLFNDPQDPV YSPNRYDKGA GYLDDGETSN
QHDDFGQASD LYVNPDPHGT DLSRAPYVKH AEDDDFIQPG ILYREVMDDG EKERLADNIT
NAMAGVSEQV EQQVYHYWDQ VDENLGKRVR ELFAEKK
//
