ID A0A1F1UPX0_9CORY Unreviewed; 772 AA.
AC A0A1F1UPX0;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=RND transporter {ECO:0000313|EMBL:OFT28146.1};
GN ORFNames=HMPREF3170_10825 {ECO:0000313|EMBL:OFT28146.1};
OS Corynebacterium sp. HMSC08D02.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=1581138 {ECO:0000313|EMBL:OFT28146.1, ECO:0000313|Proteomes:UP000177600};
RN [1] {ECO:0000313|EMBL:OFT28146.1, ECO:0000313|Proteomes:UP000177600}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HMSC08D02 {ECO:0000313|EMBL:OFT28146.1,
RC ECO:0000313|Proteomes:UP000177600};
RA Evans L.H., Alamgir A., Owens N., Weber N.D., Virtaneva K., Barbian K.,
RA Babar A., Rosenke K.;
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OFT28146.1}.
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DR EMBL; LWNU01000051; OFT28146.1; -; Genomic_DNA.
DR RefSeq; WP_070479633.1; NZ_KV789260.1.
DR AlphaFoldDB; A0A1F1UPX0; -.
DR OrthoDB; 7051771at2; -.
DR Proteomes; UP000177600; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000177600};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 15..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 187..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 312..337
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..397
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 520..541
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 546..565
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 585..605
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 626..647
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 653..676
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 47..365
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT DOMAIN 480..693
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
SQ SEQUENCE 772 AA; 83119 MW; F0F590E6BC25AD07 CRC64;
MFYRWGHFAY RQRKVLPIVV IAVIVVLQVL FGSKLGERLS QEGWEDPRAD STTAATIEND
TFGRDNAGDV ILLVRAPQGV ADPAVFNEAN RQIEALKTQF PDQIDHITSY FSAPNQQQIT
EDGTAAFAAI GLAGDGEQTL KDFRTIQPAL NDITLPGDAT VQIAGATAVA DALDTGMAND
IARAEKVGLV FVAIILLFVF GGVVAAAMPL IVGILSIIGS LSLLSILAQF QQVNIFSQSI
ITLLGLGLAI DYGLFMVSRF REELDRGVST EEAVAATTTT AGKTVFFSAL MVGVALSGLL
MFPQAFLKSV AYGAISAVML AAVISVTMLP ALFGMLGPNI DKWSVRRTSR RGRRIEDTVW
YRLPAWAMRN SKKVVVGATG ALLLLTVPMV GITFGGINES YLPPNQETRQ AQDAFNEEFP
AFRTDPIKLV VTNATNEQLV DVVLQSREVT GLAKPLSPSQ ATKDGTTVLS APLTDRNGGQ
AVVDQLRAIE APEGVGVYIA GTPAMEVESI EALLERLPWM ALYMVLATFL LMALLFGSLI
LPAKAVIMNV LGIGATLGFL TLVFVDGVGS GLLNFTPGPL MSPVLVLIIA ILYGLSTDYE
VFLVSRMVEA RHNRATTDQS IKYGTAHTGG IITAAAAIMI VVAAAFAMSD IVMMKYIAFG
MIVSLALDAT IIRLLIVPSV MHLLREDNWW APRWVKRAYR SLGEGSSSVP LVDAPSDPTH
TPVDEAIALD PSPARAGRTV NENADLVPFT ELMQELEARR ALEQLKKREL ER
//
