ID A0A1F1UUZ9_9CORY Unreviewed; 887 AA.
AC A0A1F1UUZ9;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Ribonuclease E {ECO:0000313|EMBL:OFT29937.1};
GN ORFNames=HMPREF3170_05710 {ECO:0000313|EMBL:OFT29937.1};
OS Corynebacterium sp. HMSC08D02.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=1581138 {ECO:0000313|EMBL:OFT29937.1, ECO:0000313|Proteomes:UP000177600};
RN [1] {ECO:0000313|EMBL:OFT29937.1, ECO:0000313|Proteomes:UP000177600}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HMSC08D02 {ECO:0000313|EMBL:OFT29937.1,
RC ECO:0000313|Proteomes:UP000177600};
RA Evans L.H., Alamgir A., Owens N., Weber N.D., Virtaneva K., Barbian K.,
RA Babar A., Rosenke K.;
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OFT29937.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LWNU01000024; OFT29937.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F1UUZ9; -.
DR Proteomes; UP000177600; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd04453; S1_RNase_E; 1.
DR Gene3D; 1.10.10.2480; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR006847; IF2_N.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR019307; RNA-bd_AU-1/RNase_E/G.
DR InterPro; IPR004659; RNase_E/G.
DR InterPro; IPR003029; S1_domain.
DR NCBIfam; TIGR00757; RNaseEG; 1.
DR PANTHER; PTHR30001; RIBONUCLEASE; 1.
DR PANTHER; PTHR30001:SF0; RIBONUCLEASE G; 1.
DR Pfam; PF04760; IF2_N; 1.
DR Pfam; PF10150; RNase_E_G; 1.
DR SMART; SM00316; S1; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS50126; S1; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000177600};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 261..344
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT REGION 45..203
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 644..887
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..91
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 92..121
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 138..173
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 183..203
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 647..662
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 673..727
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 738..781
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 790..827
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 851..869
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 870..887
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 887 AA; 99782 MW; 90F8117628AB6E96 CRC64;
MRVFQLAKAL GVASKDVVVA LTELGITKVA QSSVTREEAE KVIDALQQPA DKAEAKKSKD
SSDEKIRERV RKDVENEIHQ IEEKVDATFE VADEPEPEPT PEPEPEPEPE QEPEPDPEEE
ATVEYAPIFK APTRPKRRRA VRTSEPKEAD EDAAPKGEVE EPKEEEPKVE VIDEPKGISG
SARLEAQRRR RSERREAERQ RSRIVSEAEF LARRESVHRT MVVRERDRND GPGRITQVAV
LEDGLLAEHF VSTDDNASII GNIYMGRVQN VLPGMEAAFI DIGTGRNAVL YASEVDWKAA
KLGGKKRRIE HALKSGDQVM VQVSKDINGH KGARLTTHIS LAGRFLVYVP GGRNAGISRK
LPVTERKRLK GILNEVVPGK GGAIIRTAAE GMSKEAIAED VQRLHKQWEM VQEKAEAAKN
GKGSRPVLLY EEPRLIVRVV RDVFNEDFSE LIIDGKKSYN IAHAYLQSVA PDLLDRVTKF
DRSEHDGADA FAEHRIDEQV QKALARVVWL PSGGTLVIER TEAMTVIDVN TGKFTGSGGN
LEETVTANNL EAAEEVVRQL RLRDIGGMVV IDFIDMILDE NKELVLRRLK ETLGRDRSRH
QVSEVTSLGL VQLTRKKLGD GLLETYSKPC ECCGGRGVII TEEPVEHATY NPEEDDLQHR
GGRGKRRGKS NGERSNKKAE EKRRSKLDEK AIDELVGSVV SEDNEAHEDN DEPKPPTVGE
SSKRESGSRR RGRRGTSRGR GRAQEQDKPQ DKPQEQAQEK GKSEQTYEEA VDAFERSPRR
KRATRGNSRS DHKPKREDFE RQEHVKEPVK EAPREEAQEQ PKAKVTESPR RRGRRRAVRK
TSQPQQQEQP KAKETKQKAT KPATKKQESK ASARRRRRRA TRRTSSK
//
