ID A0A1F2P9B7_9EURY Unreviewed; 896 AA.
AC A0A1F2P9B7;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=SCAL_001720 {ECO:0000313|EMBL:OFV67186.1};
OS Candidatus Syntrophoarchaeum caldarius.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinales incertae sedis; ANME-2 cluster;
OC Syntrophoarchaeum.
OX NCBI_TaxID=1838285 {ECO:0000313|EMBL:OFV67186.1, ECO:0000313|Proteomes:UP000186940};
RN [1] {ECO:0000313|EMBL:OFV67186.1, ECO:0000313|Proteomes:UP000186940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BOX2 {ECO:0000313|EMBL:OFV67186.1};
RA Laso-Perez R., Richter M., Wegener G., Musat F.;
RT "Microbial consortia oxidize butane by reversing methanogenesis.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OFV67186.1}.
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DR EMBL; LYOS01000007; OFV67186.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F2P9B7; -.
DR STRING; 1838285.SCAL_001720; -.
DR PATRIC; fig|1838285.3.peg.1748; -.
DR Proteomes; UP000186940; Unassembled WGS sequence.
DR GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR CDD; cd18794; SF2_C_RecQ; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR006293; DNA_helicase_ATP-dep_RecQ_bac.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR018982; RQC_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR01389; recQ; 1.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00570; HRDC; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR Pfam; PF09382; RQC; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00341; HRDC; 1.
DR SMART; SM00956; RQC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:OFV67186.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000186940}.
FT DOMAIN 268..436
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 457..606
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 761..841
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
SQ SEQUENCE 896 AA; 103967 MW; 4A02EBE3F24490B0 CRC64;
MVITDLSRME GDRVCIFGID EERRPIRPVI SYRGVRESDL FDEEGNQIIK PFAEVEFDFL
HPLPKPPHTE DWEINTIYKP RLIKNLSEDE RKVFLEEVLD GSVKEIFGAV IHENRYINPW
EGERSLGTVK IKEVLDVNYS MKEEGKYKYR LKFLDVAGDA YDLPVTDCAF RRYCDHERIQ
NQKSMGLIGA ELQRRFNQSK VYLRVGLARP FPEKYYRCYL QISGLYTFPD YKGEDGDCGN
EVDMESAHQA LQKYFGYTSF LPLQKDIIRD VLLKNDIFVL MPTGGGKSLC YQLPALLLDG
VTVVISPLIA LMKDQVDDLR ANGIAAACIN SSLSPDEIQA VKTKLLKNRI KILYVAPERM
MQPGFLSFLQ RLNIGPIAVD EAHCISEWGH DFRPEYRRLS LLKEIFPQTP LIALTATAIT
AVQRDIIREL RLNDPKIYKA SFNRKNLFYQ VKPKYDGYSQ LIQYLENHKG DSGIIYCQSR
KSADELANKL QKERYRVLPY HAGLSSDLRN ETQNKFVKDD FEIIVATIAF GMGIDKSNIR
FVVHYDLPKN LESYYQETGR AGRDGDKADC ILFFSRGDKA KIEYFIEQKS EERERRIAYK
KLHDMVEFCE SQGCRRKILL KYFGEAYDKT NCGSCDNCIE PKEKIDGTNI AQKIILCVSQ
VKERFGVNYI ADVLCGSKSQ KIIRNRHDIL SIYGTGREYS RKRWQTFTRE LIQLGFLRLE
GDRYPIVKLT QKSQDILSGE EQVLLTRPVE EVRITEKSAD EDFDHDLFEM LRGLRKRLAD
AEGMPPYIIF HDSSLKAMAR YFPQTLSDFR KIDGVGESKL EKYGEIFVKE IADYCQDYRI
EHIRKVHPRA YEPWTKDEDE RLIREYRSGK SIEELMELFG RQSGGIKSRL KKLGLH
//
