ID A0A1F2PEM0_9FIRM Unreviewed; 248 AA.
AC A0A1F2PEM0;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Thymidylate synthase 1 {ECO:0000313|EMBL:OFV69718.1};
DE EC=2.1.1.45 {ECO:0000313|EMBL:OFV69718.1};
GN Name=thyA1 {ECO:0000313|EMBL:OFV69718.1};
GN ORFNames=ACWI_28560 {ECO:0000313|EMBL:OFV69718.1};
OS Acetobacterium wieringae.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Acetobacterium.
OX NCBI_TaxID=52694 {ECO:0000313|EMBL:OFV69718.1, ECO:0000313|Proteomes:UP000176244};
RN [1] {ECO:0000313|EMBL:OFV69718.1, ECO:0000313|Proteomes:UP000176244}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 1911 {ECO:0000313|EMBL:OFV69718.1,
RC ECO:0000313|Proteomes:UP000176244};
RA Poehlein A., Bengelsdorf F.R., Schiel-Bengelsdorf B., Duerre P., Daniel R.;
RT "Genome sequence of Acetobacterium wieringae DSM 1911.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OFV69718.1}.
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DR EMBL; LKEU01000037; OFV69718.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F2PEM0; -.
DR STRING; 52694.ACWI_28560; -.
DR OrthoDB; 1777226at2; -.
DR Proteomes; UP000176244; Unassembled WGS sequence.
DR GO; GO:0004799; F:thymidylate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.572.10; Thymidylate synthase/dCMP hydroxymethylase domain; 1.
DR InterPro; IPR045097; Thymidate_synth/dCMP_Mease.
DR InterPro; IPR023451; Thymidate_synth/dCMP_Mease_dom.
DR InterPro; IPR036926; Thymidate_synth/dCMP_Mease_sf.
DR PANTHER; PTHR11548; THYMIDYLATE SYNTHASE 1; 1.
DR PANTHER; PTHR11548:SF1; THYMIDYLATE SYNTHASE-RELATED; 1.
DR Pfam; PF00303; Thymidylat_synt; 1.
DR SUPFAM; SSF55831; Thymidylate synthase/dCMP hydroxymethylase; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:OFV69718.1};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:OFV69718.1}.
FT DOMAIN 96..206
FT /note="Thymidylate synthase/dCMP hydroxymethylase"
FT /evidence="ECO:0000259|Pfam:PF00303"
SQ SEQUENCE 248 AA; 28409 MW; 6B2D90091FB4394A CRC64;
MMVTYIHETE LHKGIEAAMK ALNQADVVIG KNQDREDSLK EIHLLMDIDS VQDIKITMAM
PTGLETLVDY VLEIVEGTKD FEKDMYGYTY HDLFSQNIDF VINKLKEDPG TRQATLHVAN
QEAARLNHPP CLQLIHYTVK DGKLNTDVVF RSNDGVKAVA MNIFALIELS RMIAREAGIS
QLGSYTHHAL SFHAYSRDWK ALEGYCKSFN DRDCTIDYED YREAYDDYAD ECREKAMSLK
NAQEKKSH
//
