ID A0A1F2PGS4_9FIRM Unreviewed; 633 AA.
AC A0A1F2PGS4;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Clostridial hydrophobic W {ECO:0000313|EMBL:OFV70517.1};
GN ORFNames=ACWI_19960 {ECO:0000313|EMBL:OFV70517.1};
OS Acetobacterium wieringae.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Acetobacterium.
OX NCBI_TaxID=52694 {ECO:0000313|EMBL:OFV70517.1, ECO:0000313|Proteomes:UP000176244};
RN [1] {ECO:0000313|EMBL:OFV70517.1, ECO:0000313|Proteomes:UP000176244}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 1911 {ECO:0000313|EMBL:OFV70517.1,
RC ECO:0000313|Proteomes:UP000176244};
RA Poehlein A., Bengelsdorf F.R., Schiel-Bengelsdorf B., Duerre P., Daniel R.;
RT "Genome sequence of Acetobacterium wieringae DSM 1911.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|ARBA:ARBA00008455}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OFV70517.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LKEU01000030; OFV70517.1; -; Genomic_DNA.
DR RefSeq; WP_070371299.1; NZ_LKEU01000030.1.
DR AlphaFoldDB; A0A1F2PGS4; -.
DR STRING; 52694.ACWI_19960; -.
DR Proteomes; UP000176244; Unassembled WGS sequence.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd02619; Peptidase_C1; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR006637; ChW.
DR InterPro; IPR040528; Lectin-like.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR000169; Pept_cys_AS.
DR InterPro; IPR013128; Peptidase_C1A.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR PANTHER; PTHR12411:SF741; CATHEPSIN K; 1.
DR PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR Pfam; PF07538; ChW; 3.
DR Pfam; PF18560; Lectin_like; 1.
DR Pfam; PF00112; Peptidase_C1; 1.
DR SMART; SM00728; ChW; 3.
DR SMART; SM00645; Pept_C1; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
PE 3: Inferred from homology;
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..633
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5009478252"
FT DOMAIN 90..295
FT /note="Peptidase C1A papain C-terminal"
FT /evidence="ECO:0000259|SMART:SM00645"
SQ SEQUENCE 633 AA; 68970 MW; D17F5447B4801331 CRC64;
MKNNLKKLLS LLLTSLMLTV LIPGSAWAEE EITEPGMASL NPAFVQYLED VNAGTLNTST
SDGHGRGYIP PPLKRYEEPI DTAITSAQAL PAAFDLRDTG RITAVRSQGD YGSCWAFASL
ASLESYLKKD TTVDFSENNL MWNSGFDGSP DDGGNYSMAT AYLARWSGPV SESSDPYDTP
KKTGLSPVYH VQEVKSIPEL PSAIKQALMD GGVLYTSMYS VPLDGEEYYN PDTFAFYYDG
TEEPDHDVAI VGWDDNYSRD NFSKKPEADG AWIIRNSWGA DWGDGGYFYM SYYDTYAGSN
VTAFHNAEAT NNYSAIYQYD PLGNISAMGY TDGDNTAWGA NIFTATASDN LMAVSTYALT
PGTSAEIKVY TDVNDGKPNS GTLRTTQTET FARGGYYTID LDNPVGLVAG QKFAVVVKYR
TPGTNDSVPV ESRFENYSSA VTANPGESFT SNTGTGGWYD TSKKSLSNVC IKAFTQSRDT
FANCLYRTHV QDQGWQNWQS NGGVSGTSGE SLRLEGIEIK MDTRGYDLGI EYATHVQNQG
WQELKSNGVM SGTEGQSLRL EAIKIQLTGA DATQFDVYYR VHAQNVGWMD WASNGGEAGT
AGFGYRLEAI EIQVLPKGSP APGLTGQPFL ENK
//
