ID A0A1F2RKD7_9BACT Unreviewed; 767 AA.
AC A0A1F2RKD7;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=FtsK domain-containing protein {ECO:0000259|PROSITE:PS50901};
GN ORFNames=A3H28_17575 {ECO:0000313|EMBL:OFV94132.1};
OS Acidobacteria bacterium RIFCSPLOWO2_02_FULL_61_28.
OC Bacteria; Acidobacteriota.
OX NCBI_TaxID=1797180 {ECO:0000313|EMBL:OFV94132.1, ECO:0000313|Proteomes:UP000177212};
RN [1] {ECO:0000313|EMBL:OFV94132.1, ECO:0000313|Proteomes:UP000177212}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SUBUNIT: Homohexamer. Forms a ring that surrounds DNA.
CC {ECO:0000256|ARBA:ARBA00025923}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FtsK/SpoIIIE/SftA family.
CC {ECO:0000256|ARBA:ARBA00006474}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OFV94132.1}.
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DR EMBL; MEKR01000156; OFV94132.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F2RKD7; -.
DR STRING; 1797180.A3H28_17575; -.
DR Proteomes; UP000177212; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 3.30.980.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR025199; FtsK_4TM.
DR InterPro; IPR041027; FtsK_alpha.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR018541; Ftsk_gamma.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22683:SF41; DNA TRANSLOCASE FTSK; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR Pfam; PF13491; FtsK_4TM; 1.
DR Pfam; PF17854; FtsK_alpha; 1.
DR Pfam; PF09397; FtsK_gamma; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00843; Ftsk_gamma; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 64..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 412..615
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT COILED 489..527
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 430..437
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 767 AA; 84463 MW; 72B9649D2BA5E847 CRC64;
MGFLTPSVNR RWNEFTGLLW MALALLGVLS LGTFSPTDPS LNTATGAETV RNWVGVVGTY
TADLLYQLFG ACAFLFPISL AALGWWRFRS RGVRNRSARV SGAALFLLSL MAALALIPYP
IRLYDLFPLG GVVGILIADG LRRGLNGPGA AILLTITSLA SLYLLTTFSV ERASAWLQER
FGQRFRQRIQ WLARLQLRLA AWKQARAARS QSKIPVRASL PATSISVVQP PSVSVGAMPE
LVKSKPVEAA ILVVPPIQAP PLATRSGHRR PVARSEGHYK LPSTSLLHPP IAVPANSEDE
FKRLAMLLTA KCEEFDVRGS VTQINPGPVV TTYEFKPEAG VKYNRITNLV EDLCLALEAE
SILIERIPGK STVGIEVPNA HRETIVLREI LESESFTSAR SPLTIALGKE INGRIRVADL
ASMPHLLIAG STGSGKSVSM NSLILSILFK ATPEEVKVIM VDPKRLELGL YEGIPHLVTP
IITDPKIAAN ALRNAVREME RRLKLLAERG VRNIEQYNRL FEQKEKESLN LFEAPSEHAP
LPYIVIFIDE LADLMMVDSH NVETSITRLA QMARAVGIHL VLATQRPSVD VITGLIKANF
PARISFRVAT KVDSRTILDS NGSEALLGKG DMLYSPPGSG RLVRVHGALV TESEIAQVVE
FWRAQATPSY SEEFLLPPAG EEPEDEEEWT GERDEMFQEA VRVVLEMGKA STSILQRRLR
LGYGRAARLL DIMEKDGIIG PPDGSKPREV LKRPDWIEEF ERSQTEA
//
