ID   A0A1F3KAZ4_9BACT        Unreviewed;      1097 AA.
AC   A0A1F3KAZ4;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE            EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN   ORFNames=A2W98_07295 {ECO:0000313|EMBL:OFY25107.1};
OS   Bacteroidetes bacterium GWF2_33_38.
OC   Bacteria; Bacteroidota.
OX   NCBI_TaxID=1797342 {ECO:0000313|EMBL:OFY25107.1, ECO:0000313|Proteomes:UP000177621};
RN   [1] {ECO:0000313|EMBL:OFY25107.1, ECO:0000313|Proteomes:UP000177621}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=27774985; DOI=10.1038/ncomms13219;
RA   Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA   Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA   Williams K.H., Hubbard S.S., Banfield J.F.;
RT   "Thousands of microbial genomes shed light on interconnected biogeochemical
RT   processes in an aquifer system.";
RL   Nat. Commun. 7:13219-13219(2016).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OFY25107.1}.
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DR   EMBL; MEOF01000006; OFY25107.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1F3KAZ4; -.
DR   STRING; 1797342.A2W98_07295; -.
DR   Proteomes; UP000177621; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   InterPro; IPR011110; Reg_prop.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR011123; Y_Y_Y.
DR   PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR   PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR   Pfam; PF07494; Reg_prop; 10.
DR   Pfam; PF07228; SpoIIE; 1.
DR   Pfam; PF07495; Y_Y_Y; 1.
DR   SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 2.
DR   SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        790..807
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          719..781
FT                   /note="Two component regulator three Y"
FT                   /evidence="ECO:0000259|Pfam:PF07495"
FT   DOMAIN          895..1094
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|Pfam:PF07228"
SQ   SEQUENCE   1097 AA;  126111 MW;  EA1B0E99674FB257 CRC64;
     MSFNSIFLYS QKPSITFERL GIDQGLSQSS ANCILEDENN FLWIGTQEGL NKYYGQNFCF
     EIFKHDLVDT NSISDIWVYD IAQDKNGNIW IATRYGLNML NPKTRKIKRY FQDINEISSL
     YNNEVFSVFV DSKGGVWVKT NDVLSLLDTT SGKFTHYEHY VNYFNTRSQT RFPIIEDKNG
     LIWYGTVDGL NSFDRNFEQS KRYKFDSANP FSLSNNFVTA IFEDSKGTLW VGTQDGLNKF
     NKKKKTFERY YNIPGNENSL VNNSVKAIVE DNNGMIWVGT DGGLSILDLG NNKFYNYRNQ
     ANNPTGLSNN EILSFYKGSS DIIWIGTNGG GINKVDLKRK KFEIYRREAG ENTLNFSSNV
     IASFFIDRDS LLWVGTYGEG LNIYNRKTGH IDIYSKSTNP AIVDDYVHAI GEDSDGKIWI
     GTRNGINIYD QEKKTFSLIQ DYIPTTAKHL NLNSNRIYYF LEDRNKNMWI ASERGLIKIN
     VKTEDIKIYR KNFRDSLSLC DDRVYSIIED NEGFLWIGTT NGLNKYDPKK DVFYQYKSKL
     NSVNTISHNT IYSVFEDSEG IIWIGTAGSG LNKYDKKSDT FVYYTEKNGL PNGTIYEIEE
     DNNGDLWFST GRGLAKLDKK TNTISSFTND DGLQGLEFNN GANFKSKDGE LFFGGTNGFN
     SFYPELIKYN ENKPKTVFTY FEKTSTDGGL SRMYLDDIKE IHLSYKDHTF KIFFAALEYT
     KPEKNSYMYM MENLKDEWIS LGTQSFKTFS NIPPGEYIFH LKSSNNDLVW NEEPISIKII
     IEPPFWQTKW AYVLIILIVV GSIYYFIEVR TRKLKAANHI LREKQSAALE IARQKEELTV
     KNKNITDSIN YAKRIQEAMM PSEYLFNKLL PESFILYKPK DIVSGDFYWI TEKNNKIFVA
     AVDCTGHGVP GAFMSIIGFD LLRNITKEQG VEEPAQILNL LNEGVTETFV KNADNQQVKD
     GMDIALCVYD KENSVVEFAG ALNPFFLIRD NDIISIRGNR FSVGMVDKGV QHKFEKHVIP
     VKEGDVIYIF SDGYADQFGG PFGKKFKYSR FRQLLLTVHS LPMRKQKAFL DENIISWMGE
     LEQVDDILVI GFRINKL
//