ID A0A1F3MSZ4_9BACT Unreviewed; 375 AA.
AC A0A1F3MSZ4;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein {ECO:0000259|Pfam:PF16576};
GN ORFNames=A2X22_11215 {ECO:0000313|EMBL:OFY55428.1};
OS Bacteroidetes bacterium GWF2_49_14.
OC Bacteria; Bacteroidota.
OX NCBI_TaxID=1797354 {ECO:0000313|EMBL:OFY55428.1, ECO:0000313|Proteomes:UP000177245};
RN [1] {ECO:0000313|EMBL:OFY55428.1, ECO:0000313|Proteomes:UP000177245}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OFY55428.1}.
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DR EMBL; MEOR01000030; OFY55428.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F3MSZ4; -.
DR STRING; 1797354.A2X22_11215; -.
DR Proteomes; UP000177245; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF15; HLYD FAMILY OF SECRETION PROTEINS; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 89..291
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 31..58
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 375 AA; 41261 MW; 47AB1CD871D91505 CRC64;
MKKVIIPIVV LILSLASCQP KRTADTVSAE IGKTRTEIAA LSQKLETLEA ELVTLQPEKV
EKTVKVAISA VSRKDFADYI ISSGNVEAVK TASISPEMNG KIESIPVKEG QWVKKGQVLL
NLDSKVMKNS LAELDKSYEM VVTLYIKQKE LWDQGVGSEM QYLEIKNRKE SMERTRETLS
SQMEMTRIVA PFEGRIEKVM VKVGELATPG RGIIDLVNLD RLYINTEVSE SFLATVRKGD
TVMVEFPNLP GVTKTVPIAF TSNIINPLSR TFPIRVELQN SRGEIKPNML ASLKIRTDNQ
PRAIVVPTSM IRQDVGGSYV FVALGSGNSG TAKKTYITTG SSDGVDTVVK EGLTDSDMIV
SLGYNQIKNG TLITW
//
