ID A0A1F3MWK6_9BACT Unreviewed; 656 AA.
AC A0A1F3MWK6;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Glycosyl hydrolase family 2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=A2X22_12180 {ECO:0000313|EMBL:OFY56645.1};
OS Bacteroidetes bacterium GWF2_49_14.
OC Bacteria; Bacteroidota.
OX NCBI_TaxID=1797354 {ECO:0000313|EMBL:OFY56645.1, ECO:0000313|Proteomes:UP000177245};
RN [1] {ECO:0000313|EMBL:OFY56645.1, ECO:0000313|Proteomes:UP000177245}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OFY56645.1}.
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DR EMBL; MEOR01000009; OFY56645.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F3MWK6; -.
DR STRING; 1797354.A2X22_12180; -.
DR Proteomes; UP000177245; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0001681; F:sialate O-acetylesterase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1110; SGNH hydrolase; 2.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR005181; SASA.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR039329; SIAE.
DR PANTHER; PTHR22901; SIALATE O-ACETYLESTERASE; 1.
DR PANTHER; PTHR22901:SF0; SIALATE O-ACETYLESTERASE; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR Pfam; PF03629; SASA; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF52266; SGNH hydrolase; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..656
FT /note="Glycosyl hydrolase family 2"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5009494077"
FT DOMAIN 275..370
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 442..543
FT /note="Sialate O-acetylesterase"
FT /evidence="ECO:0000259|Pfam:PF03629"
SQ SEQUENCE 656 AA; 72391 MW; A332DF46DCCC1EA0 CRC64;
MKKNLGLSFV FLLSSFFFSY AFGQTKLPAV IGSHMVLQQQ SVAPIWGWAR AGETVSVKPS
WDSQVVSTVA GADGKWMVRV KTPAAGGPYT IEISGKKKTV LEDILIGEVW VCSGQSNMEM
PLRGWPEWGG PIDNSAAEIA GANYPNIRLF TVPRVFADKP LDDCKGKWLA CTPETIKDFS
ATGYFFGREL YKNLNIPIGL VFTSWGGTVA EAWMSEEFAA TIPAFTTEPG KLDVQKFKAA
KLEDFNKRQA EWAASIGFQP GDKAPEWAVK ATADASWKEM PVPGEWSKTG IGAHTGLVDY
RLVFKVPDSW VGKELVLELG PIDEMDITWV NGKLVGSHLN VSDWATNRVY EIPAGIVQKG
DNILAVQVAN TSGLGGINGK PEMLKISPKK SKKGQPLAGN WQVCKGGAFS LVKPMPDCVD
CGEPNLPTVL YNGMIAPIVP FSIKGAIWYQ GESNRYDGEL YKKIFPKMIV NWRHDWNRGE
FPFYFVQIAP YTYQDAYSTG LLREAQDFTM RTLPNTGMVV TMDIGNLKNI HPANKQDVGK
RLAFWALAKD YGKKDVVFSG PIFKSFVREG NKIRIWFDYT EGGLKTDGKE LKHFTVAGAD
HQFKPAKAVI EGNTVVVYSE QVARPEEVRF GWGSTDVTNL FGPSGLPAGP FRTDVR
//
