ID A0A1F4BBY1_9PROT Unreviewed; 294 AA.
AC A0A1F4BBY1;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=NAD(P)-dependent oxidoreductase {ECO:0008006|Google:ProtNLM};
GN ORFNames=A3I02_15705 {ECO:0000313|EMBL:OGA21892.1};
OS Betaproteobacteria bacterium RIFCSPLOWO2_02_FULL_67_26.
OC Bacteria; Pseudomonadota; Betaproteobacteria.
OX NCBI_TaxID=1797492 {ECO:0000313|EMBL:OGA21892.1, ECO:0000313|Proteomes:UP000178840};
RN [1] {ECO:0000313|EMBL:OGA21892.1, ECO:0000313|Proteomes:UP000178840}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGA21892.1}.
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DR EMBL; MERD01000098; OGA21892.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F4BBY1; -.
DR STRING; 1797492.A3I02_15705; -.
DR Proteomes; UP000178840; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43060; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED; 1.
DR PANTHER; PTHR43060:SF15; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027}.
FT DOMAIN 1..151
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 154..273
FT /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF14833"
FT ACT_SITE 160
FT /evidence="ECO:0000256|PIRSR:PIRSR000103-1"
SQ SEQUENCE 294 AA; 31647 MW; 74CD2266E18ED3D1 CRC64;
MGGAFARHLL AAGFNVIGYD PVPAAGRALA RAGGRSAGSG AEVAAKARII ITSLPSPAAM
EEAYFGKRGI AAGARPGTIV IEASTMTLEL KESLRRRLAR RRVMLLDCPI SGTGAQAAAK
DIAIYASGDR RAFNRCRGVF NGFARSTYYC GAFGIGSKLK FVANLLVTIH NLSTAEAMVV
GEKAGIDLGL LYRVIADGAG SSRMFQVRGP MMVRGHYLPP HMKSKIYQKD IGIIRAFVRR
LKCPTPLFDG SIPYYTAALR QGWSLHDTAA IHSVLRKRAG LRGKPRRRTT RKGR
//
