ID A0A1F4EJ51_9PROT Unreviewed; 380 AA.
AC A0A1F4EJ51;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=DNA methylase {ECO:0000313|EMBL:OGA61178.1};
GN ORFNames=A3F77_10265 {ECO:0000313|EMBL:OGA61178.1};
OS Betaproteobacteria bacterium RIFCSPLOWO2_12_FULL_67_28.
OC Bacteria; Pseudomonadota; Betaproteobacteria.
OX NCBI_TaxID=1797503 {ECO:0000313|EMBL:OGA61178.1, ECO:0000313|Proteomes:UP000177406};
RN [1] {ECO:0000313|EMBL:OGA61178.1, ECO:0000313|Proteomes:UP000177406}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGA61178.1}.
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DR EMBL; MERO01000180; OGA61178.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F4EJ51; -.
DR STRING; 1797503.A3F77_10265; -.
DR Proteomes; UP000177406; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0034470; P:ncRNA processing; IEA:UniProt.
DR GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR PANTHER; PTHR47313; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L; 1.
DR PANTHER; PTHR47313:SF1; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L; 1.
DR Pfam; PF02926; THUMP; 1.
DR Pfam; PF01170; UPF0020; 1.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51165; THUMP; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:OGA61178.1};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00529};
KW Transferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000313|EMBL:OGA61178.1}.
FT DOMAIN 44..155
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
SQ SEQUENCE 380 AA; 41509 MW; 4CE35C060276AA4D CRC64;
MSEQFFAPCP RGLEALLAEE LSALGAAGAA SVPGGVAFGG GWAVCYAANL HSRLASRVLW
RVAEFDYRNE NDVYEAARAV DWPARFAAGR TLRVNVTAQA SPLRSIEFIT LRIKDAICDR
WRADTGSRPS IERARPDVRV HAFLERDRGT LYLDTSGEPL FKRGWRRHTV EAPLRENLAA
GIVLLTGWTP AEPLLDPMCG GGTLLVEAAA IGLGVAPGAG RSFGFEKLSN FDAKLLQRLK
STAGENRSST RLELYGSDRD ARALEAATKN LSAAGFAGQV RLERADILAR SAPAASGVML
ANPPYGERIG SEEELARFYP KLGDALKKNF AGWRCHFFTA DLRLAKLIRL QPARRVPLFN
GALECRLYEF RIVAGSHRRA
//
