ID A0A1F4EZL9_9PROT Unreviewed; 408 AA.
AC A0A1F4EZL9;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Magnesium transporter {ECO:0000313|EMBL:OGA66573.1};
GN ORFNames=A3G83_09470 {ECO:0000313|EMBL:OGA66573.1};
OS Betaproteobacteria bacterium RIFCSPLOWO2_12_FULL_68_20.
OC Bacteria; Pseudomonadota; Betaproteobacteria.
OX NCBI_TaxID=1797505 {ECO:0000313|EMBL:OGA66573.1, ECO:0000313|Proteomes:UP000178578};
RN [1] {ECO:0000313|EMBL:OGA66573.1, ECO:0000313|Proteomes:UP000178578}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SLC41A transporter family.
CC {ECO:0000256|ARBA:ARBA00009749}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGA66573.1}.
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DR EMBL; MERQ01000077; OGA66573.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F4EZL9; -.
DR STRING; 1797505.A3G83_09470; -.
DR Proteomes; UP000178578; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR CDD; cd04606; CBS_pair_Mg_transporter; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.357.20; SLC41 divalent cation transporters, integral membrane domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR006669; MgtE_transporter.
DR InterPro; IPR006667; SLC41_membr_dom.
DR InterPro; IPR036739; SLC41_membr_dom_sf.
DR PANTHER; PTHR43773; MAGNESIUM TRANSPORTER MGTE; 1.
DR PANTHER; PTHR43773:SF1; MAGNESIUM TRANSPORTER MGTE; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF01769; MgtE; 1.
DR SMART; SM00116; CBS; 2.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF161093; MgtE membrane domain-like; 1.
DR PROSITE; PS51371; CBS; 2.
PE 3: Inferred from homology;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 241..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..333
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 345..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 384..407
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 94..156
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 157..213
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 408 AA; 43429 MW; 67F5C3417B662458 CRC64;
MDDLDRPTIQ RSAADLADEV KLRSAHGAAV KLAHFGGAEI AAALLRLSPA FAQDVLAALP
AEARERALNA APPESASQWQ RNALYEEGTI GRMMEPVLAA YLPEDTVGGT IESLREMVKT
AFITYIYVVD PAERLLGIVT MRDLLFRDHH QTLGEVMLHD VFSLHASMPL EETMKSVLER
HFPVYPVVDA ENRLIGLVRG QSIFEAQAIE ISLQAGTMVG VEKEERLATP WPLSLRLRHP
WLQLNLLTAF LAAAVVGIFQ GTIDRLVILA LFLPVLAGQS GNTGCQALAV TLRGITLGEL
KPGSERALVA KEAGLGALNG AGVGLLAAIG MTITAAGQNA EHPFILGLVV FLAMVGSCVA
SGISGAMVPL TLKRFGFDPA TASSIFLTTA TDVVSMGMLL GLATILVR
//
