ID A0A1F4I157_9BURK Unreviewed; 1074 AA.
AC A0A1F4I157;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=NAD-binding oxidoreductase {ECO:0000313|EMBL:OGB03871.1};
GN ORFNames=A3E25_09135 {ECO:0000313|EMBL:OGB03871.1};
OS Burkholderiales bacterium RIFCSPHIGHO2_12_FULL_69_20.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales.
OX NCBI_TaxID=1797561 {ECO:0000313|EMBL:OGB03871.1, ECO:0000313|Proteomes:UP000177017};
RN [1] {ECO:0000313|EMBL:OGB03871.1, ECO:0000313|Proteomes:UP000177017}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGB03871.1}.
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DR EMBL; MESD01000048; OGB03871.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F4I157; -.
DR Proteomes; UP000177017; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd00207; fer2; 1.
DR CDD; cd06185; PDR_like; 1.
DR Gene3D; 3.10.20.30; -; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR036010; 2Fe-2S_ferredoxin-like_sf.
DR InterPro; IPR001041; 2Fe-2S_ferredoxin-type.
DR InterPro; IPR006058; 2Fe2S_fd_BS.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR012675; Beta-grasp_dom_sf.
DR InterPro; IPR017927; FAD-bd_FR_type.
DR InterPro; IPR039261; FNR_nucleotide-bd.
DR InterPro; IPR028894; RDH_dom.
DR InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR PANTHER; PTHR47354:SF1; CARNITINE MONOOXYGENASE REDUCTASE SUBUNIT; 1.
DR PANTHER; PTHR47354; NADH OXIDOREDUCTASE HCR; 1.
DR Pfam; PF13486; Dehalogenase; 1.
DR Pfam; PF12838; Fer4_7; 1.
DR PRINTS; PR00409; PHDIOXRDTASE.
DR SUPFAM; SSF54292; 2Fe-2S ferredoxin-like; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
DR PROSITE; PS00197; 2FE2S_FER_1; 1.
DR PROSITE; PS51085; 2FE2S_FER_2; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 1.
DR PROSITE; PS51384; FAD_FR; 1.
PE 4: Predicted;
KW 2Fe-2S {ECO:0000256|ARBA:ARBA00022714};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 545..575
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 752..857
FT /note="FAD-binding FR-type"
FT /evidence="ECO:0000259|PROSITE:PS51384"
FT DOMAIN 986..1074
FT /note="2Fe-2S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51085"
SQ SEQUENCE 1074 AA; 117406 MW; 5C7BEEE94E29F998 CRC64;
MRFFSYQDRP VHLGPYPLER LTRTADAPDL QAVPALQPVD FDAPDALSIA HAMKRYIGMF
DVVRDGAVAA LPAEAPTDPT ERAQHLKAAG YYFDASMMGI CQLSAAALRA QPLRNPAVAG
IADELARSQP QSFAAGMDMI LADVLESART LHGPIDHHTH AIVIAVEFQR DPRPGEPGSD
WIAGTQAQRA AVLAAQTAVL LSTYLRLLGF EARAHSATCS EVDLNRLAVA AGLAHADLSH
PYLGTRFGLA AVSTTFQMAV DEALAPPAQQ DRRRSHGLAW QLGMGTLKSA IHQDPYARRD
FRLGPHPFET LQRRDEPTTF IDHARVPRFP KRADFFARAL FGDLGRDVQA SAKNAHYVMK
SPIGACARRA LGALLLLQFG EARGPVSPTV ADPQRNADNL KATAYYLGCD AVGLCAVPEW
AYYSHDAGGN ALPAYHANGI NLLLDQGHET MEGASGDDWI SVAQSMRAYL RFSLLGGIVA
EQVRRLGYSA RVHSVLDGDV LQPPLLLLSG LGEVSRIGEV ILNPYLGPRL KSGTVTTDLP
MVMDRPIDFG LQRFCEQCNK CARECPSGAI TAGPKRMYNG YEIYKSDAEK CARYRITNAG
GGMCGRCMKT CPWNLEGLFA DSAFRWLAMH LPGQARHLAA LDDHWGRGRI NPVKTWWWDL
ELDRGTQRYV QAKLTHRREL NIGLKIDPAL QSLAVYPADQ MPPPYPVAFP VDREQGIARY
RALLSPAQYR EKLARGDTAD LAPPFQLPAG EPPVFPVLLQ RREDMAPDVA KYEFVARDGG
QLPPFEAGAH IDVVIAPEYL RPYSLAGDPA DRSKWVLGVQ REAPEHGGRG GSALMHRAFR
AGRMVFVSKP NNLFKLHEEA TMSWLFAGGI GVTPLLTMAH RLHAIGKPFE LHYSAASRGT
AGFVADIEAA AWHAQAHCHF KDEGRRADLP RLIPPHTPGA HLYTCGSARY MDSIFDTARA
AGWPDEALHR EFFSVPEAPP RENHAFTLRL LASGRTLEVP AERCATEVLA AAGLKVDVKC
SDGLCGVCAL AYDPAASDQI DHRDVVLSTA ERRERVILCC ARTVQPGGVI ALRL
//
