ID A0A1F4JL64_9BURK Unreviewed; 741 AA.
AC A0A1F4JL64;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Guanylate cyclase {ECO:0000313|EMBL:OGB23031.1};
GN ORFNames=A3I66_08400 {ECO:0000313|EMBL:OGB23031.1};
OS Burkholderiales bacterium RIFCSPLOWO2_02_FULL_57_36.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales.
OX NCBI_TaxID=1797562 {ECO:0000313|EMBL:OGB23031.1, ECO:0000313|Proteomes:UP000176765};
RN [1] {ECO:0000313|EMBL:OGB23031.1, ECO:0000313|Proteomes:UP000176765}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGB23031.1}.
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DR EMBL; MESE01000096; OGB23031.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F4JL64; -.
DR STRING; 1797562.A3I66_08400; -.
DR Proteomes; UP000176765; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR007890; CHASE2.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR PANTHER; PTHR43081:SF16; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC; 1.
DR PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR Pfam; PF05226; CHASE2; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM01080; CHASE2; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 368..390
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 397..418
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..444
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 486..618
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 741 AA; 82351 MW; 17F13C1800EFB4F8 CRC64;
MRQHVIRFAL GLLILLVLLL HAGEIYKLSV ISSLDQRLYD TKIQLTMPKT VDERLVILDI
DEKSLAEIGR WPWGRDRMAT LVNKLFDQYG IRALGFDVFL AEPDESSGLR VLEELGGNRL
KNNQQYLATL TQLRPQLDYD KLFAKSLQGR PVILGYYFAN EGSNSGAIPP PVLTGPALKG
RDSAVFTWSN YGGILPQFQQ VSMGAGYVNP DTESDGSVRR VPLLVKYDQN FYESFSLAMV
RALLGSPDIV PGIDGADGSS SDGYGAIDWL DLPTTRGTMR IPVDGNMAAL VPYRGYVKSY
RYYSIADILA DRIKPEQLQG RIALVGTSAP GLTDERTTPV GKVYPGVEVH ANLITGMLDN
TIKLKPQYAV AVEFIFLLLV GGLMIFLFPW RSPLRATLAT LLVLVAVLGT NLGLWQYANW
VQPLAASLLL VSGLFVLNMS YGYFVESRAK RQFTELFGQY VPPELVEEMS RNPQSYSMAG
RKAELTVLFS DIRGFTAMSE RMEPDQLAYL MNEYLSAMTL VIRRHRGTLD KYIGDAIMAF
WGAPVSDSGH ARNAVVTALE MLQALVELNR NLITKGMPEI KIGIGINTGS MTVGDMGSVV
RKAYTVMGDA VNLGSRLESI TKQYGVGIIV GEATRRAVDD ILFKELDLVQ VVGKEEPVAI
FEPLGRKGQL SEDALEELDL WNQLLQHYRK QAWQQADSVL DTLVQMQPDC RLYELYRERI
AAFRKDAPNA AWAGVTRLDT K
//
