ID A0A1F4JTC4_9BURK Unreviewed; 1050 AA.
AC A0A1F4JTC4;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Diguanylate cyclase {ECO:0008006|Google:ProtNLM};
GN ORFNames=A3I66_23255 {ECO:0000313|EMBL:OGB25562.1};
OS Burkholderiales bacterium RIFCSPLOWO2_02_FULL_57_36.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales.
OX NCBI_TaxID=1797562 {ECO:0000313|EMBL:OGB25562.1, ECO:0000313|Proteomes:UP000176765};
RN [1] {ECO:0000313|EMBL:OGB25562.1, ECO:0000313|Proteomes:UP000176765}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGB25562.1}.
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DR EMBL; MESE01000044; OGB25562.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F4JTC4; -.
DR STRING; 1797562.A3I66_23255; -.
DR Proteomes; UP000176765; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd12914; PDC1_DGC_like; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF08448; PAS_4; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 14..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 645..779
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 788..1042
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 1050 AA; 116715 MW; ED8FC6058BA21DD1 CRC64;
MLARSAERVL EPHIFFPALA LVLLGVVWSV AFQLIRIEGE RAVRTAIDSS VELIETYEAQ
MVRNLAAINQ TLSTAKYAYE FKRTPAILAE MNQKSLLPPA LIFTVGITDR SGEVVASTRP
DALDSVGGQQ FFRAHQARDS DMPFVSSPMR AVGNDEWQVM FTRRLNAADG SFDGIVMVSV
DPAYFTSGYE RSRLGDQGLL GLLAADGVFL AKRTGEKVSW GESADIVVNN IGSEWQARPA
IVNPWDGVRR YTHTSRIHGF PLSVVVGLSE EEQLAPFEEN KRGYLWKAVA VSALVLAVVA
ALGFLSWQLT TNRRRTRKAQ ETYYAASDAS LDAFFVLRSV RNAEGRIEDF ILDDTNRRGA
AMFGYPKEKV IGRSLTRAFP ETRRNGAFEE YVRVAENKSM HEKEWENEYP GLRAGWLHRQ
LVAVEDGLVV IMRDISERKH AEALLTGQAR ALEMIATGTP LPEVLQNLLH LIASQVPGMM
GSILLLDKDG EHLSHGSAVN LPQEYTQAID GVAIGPQVGS CGTAVYRREP VIVTDIQQDP
LWADYRDLAN EHGLRACWSI PILSHQDCVL GTFAMYYRDV REPTALDRQL VGIAARIAGI
AIERKQSEDR IHYMAHHDPL TGLPNRSLLD DRVEQAMLYA QRYDRQLTVM FIDLDNFKLV
NDSLGHNAGD ELLKTVARRM VQSVRSTDTV LRLGGDEFVI VLLDQAGSAS ALSSPLQKLH
EAIAQPMTLV GKEVRITCSM GLATYPEDGT DSDTLLMHAD AAMYRAKELG RNNYQFYTAD
MNRQIHEKLA LQEGLRNAIM RDELFLVYQP QVDMRSGKII GMEALIRWQH PELGVVSPVK
FIPLAEETNL IVSIGDWVLH TACKQNKAWQ EAGMPPIVVS ANVSARQFKE GDLVSRVARA
LEESGLHPKY LALELTESLI MQDLQQALET MAKLQAMGVQ MSIDDFGTGY SSLSALKKFP
IARLKLDRSF VSDLPHDQDD KAIAMAVISL GHQLNLRIVA EGIETHEQFV FLRDNGCDEM
QGDYFSKPVL PEEIIALCGK QASLVLEGAA
//
