ID A0A1F4KJ89_9BURK Unreviewed; 639 AA.
AC A0A1F4KJ89;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=diguanylate cyclase {ECO:0000256|ARBA:ARBA00012528};
DE EC=2.7.7.65 {ECO:0000256|ARBA:ARBA00012528};
GN ORFNames=A3F78_01415 {ECO:0000313|EMBL:OGB34562.1};
OS Burkholderiales bacterium RIFCSPLOWO2_12_FULL_61_40.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales.
OX NCBI_TaxID=1797566 {ECO:0000313|EMBL:OGB34562.1, ECO:0000313|Proteomes:UP000178940};
RN [1] {ECO:0000313|EMBL:OGB34562.1, ECO:0000313|Proteomes:UP000178940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGB34562.1}.
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DR EMBL; MESI01000017; OGB34562.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F4KJ89; -.
DR STRING; 1797566.A3F78_01415; -.
DR Proteomes; UP000178940; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 2.60.40.2380; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR011623; 7TMR_DISM_rcpt_extracell_dom1.
DR InterPro; IPR011622; 7TMR_DISM_rcpt_extracell_dom2.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF07695; 7TMR-DISM_7TM; 1.
DR Pfam; PF07696; 7TMR-DISMED2; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..639
FT /note="diguanylate cyclase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5009511760"
FT TRANSMEM 195..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 223..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 255..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..334
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 346..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 377..395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 496..631
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 639 AA; 71655 MW; 43FFADB3EB66B8C6 CRC64;
MNLKSFCRLL APLLIALWFL APIAAQAQPD ATFPVFEVSR NTPGRMDVES RMGVLVDASR
DLTAGQVTAP GQHWQSISRP SPNFGFTQDA YWFRFQINNP NPQELTRFIE LPIPFIDDVR
LHHYAGGVLR THYALGDELP FARRVVMHRN FVMPVNLAPG GNLIYIRLAS SGTIEAPFRI
WDPVQFHAAS NDENLLQGTV IGVLLIMIAY NLFIFFSTRN INYIYYIGFV ASYLLFHLTL
TGYTFAYVWP HAVRWNSFAI SSFMASSMLF TCLFAGRFLK LRQFSMPAFY WVRALTLLSA
LLLALTFVLP YSLTVRIGAA VTLPMAITAL VLGYWRWWTG AKFARFYCLA WTAILIGLCV
LNASKQGWIP LNGWTENASE IGIVLLVMLL SFTLADQINN DRTLRLNAQA AALAHERHAR
ATQQALIRAT EDANRELELR VQSRTLDLHA TLEQLKDAND RLQLLSTTDG LTQISNRAYF
DTALALEFRR AVRQKCALTL VMFDIDHFKH VNDTYGHLAG DACLRALADR LRPRINRAGD
VFARFGGEEF VVVLTASDLA SAIALTEEFR AAIESLRVEF EGQTIQFTAS FGIASAIPQP
PLCAQDYLAA ADKALYQAKH DGRNCVRSAT LPHTTSEPL
//
