ID A0A1F4QAK6_9BACT Unreviewed; 478 AA.
AC A0A1F4QAK6;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Glutamate synthase {ECO:0000313|EMBL:OGB92978.1};
GN Name=gltD {ECO:0000313|EMBL:OGB92978.1};
GN ORFNames=A3H39_13320 {ECO:0000313|EMBL:OGB92978.1};
OS candidate division NC10 bacterium RIFCSPLOWO2_02_FULL_66_22.
OC Bacteria; candidate division NC10.
OX NCBI_TaxID=1801658 {ECO:0000313|EMBL:OGB92978.1, ECO:0000313|Proteomes:UP000177374};
RN [1] {ECO:0000313|EMBL:OGB92978.1, ECO:0000313|Proteomes:UP000177374}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGB92978.1}.
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DR EMBL; METH01000102; OGB92978.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F4QAK6; -.
DR STRING; 1801658.A3H39_13320; -.
DR Proteomes; UP000177374; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0016639; F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0006537; P:glutamate biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR028261; DPD_II.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR006005; Glut_synth_ssu1.
DR InterPro; IPR009051; Helical_ferredxn.
DR NCBIfam; TIGR01317; GOGAT_sm_gam; 1.
DR PANTHER; PTHR43100; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR PANTHER; PTHR43100:SF1; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR Pfam; PF14691; Fer4_20; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR PRINTS; PR00419; ADXRDTASE.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR SUPFAM; SSF51971; Nucleotide-binding domain; 2.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Glutamate biosynthesis {ECO:0000256|ARBA:ARBA00023164};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 25..131
FT /note="Dihydroprymidine dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF14691"
FT DOMAIN 145..460
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
SQ SEQUENCE 478 AA; 52865 MW; A958C8FEF82BCF73 CRC64;
MGKPTGFLEF TRAKQPYRPV EERIRDWTQV MLPWPVATLQ QQGARCMDCA VPFCHQGCPL
GNIIPDWNDL VYRDRWREAI DRLHATNNFP EFTGTLCPAP CEGSCVLGIN DDPVTIKAIE
LAIINHAFEA GWITPEPPLS RTGKTVAIVG SGPAGLAAAQ QLNRAGHRVT VLERADRIGG
LLRYGIPEFK MEKRVLDRRL EILRKEGITF RVNANVGVNV PVETLRGEFD TILLAGGSTL
PRDLKVPGRE LRGIHFAMEY LPLQNRRCEG DQTPEGEFIT AKGKRVVIIG GGDTGADCLG
TVHRQGAASV HQFELLPMPP KERAPDNPWP LWPNIFRTSA AHEEGGIRDY CISTTRFSGR
DGCVERLHAL RVEFVSDGNG RPTMREIPGS AFEMEVDLVL LAMGFLGPER GGMLDQLGVK
LTERGNVWRD ETWMTSVPGV FTAGDMQRGQ SLIVWAIAEG RQAARGIDQY LMGSTNLP
//
