ID A0A1F4QFQ6_9BACT Unreviewed; 667 AA.
AC A0A1F4QFQ6;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=Guanylate cyclase domain-containing protein {ECO:0000259|PROSITE:PS50125};
GN ORFNames=A3H39_07525 {ECO:0000313|EMBL:OGB94834.1};
OS candidate division NC10 bacterium RIFCSPLOWO2_02_FULL_66_22.
OC Bacteria; candidate division NC10.
OX NCBI_TaxID=1801658 {ECO:0000313|EMBL:OGB94834.1, ECO:0000313|Proteomes:UP000177374};
RN [1] {ECO:0000313|EMBL:OGB94834.1, ECO:0000313|Proteomes:UP000177374}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGB94834.1}.
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DR EMBL; METH01000024; OGB94834.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F4QFQ6; -.
DR STRING; 1801658.A3H39_07525; -.
DR Proteomes; UP000177374; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR007890; CHASE2.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR Pfam; PF05226; CHASE2; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM01080; CHASE2; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 332..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 442..574
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 667 AA; 73175 MW; 6037728729540D9F CRC64;
MRIRLPELRS RGRRFVLGLS WGFLASGAVA IATSLGYFSG YQGKALDLYF WAQGRTRAPE
IVLVAIDDVA FQRLNERQPL PREYLAGVIR GLRKSGARLI GLDVDLRRPT NPADDRALLA
AIRGAPGDPA GPVVVARTLT VASDSAGEIR YRPMPLYEPL LEMASGFAEV PKDDDGFFRR
IPLVVPLGDG QVLPSLSLRL LARLGGLDPA AFARTLAGPE PVDLSLPEWD EPRGTLRQAS
PLRFFRDDDW KINYIGPAGS LLTIGSDAVY QLGISDQEVA RENPLRDRIV LVGATFAESR
DAFPTPRGIM YGVEIHANIL HTLLTRSQIQ PVAWGASLLL QFILCLALSA LFALLRPNRA
LIISLGTAAL AAVGISAWPA AHGAYWFDLL TPILAIRLAA SLHDAVERRR IRRSFHQYIG
REVADRVYQD DPALAGQRRT VSILFTDLRD FTTMSETMAA DQVAQQLNEY FPMMVEAVQR
HRGIINDFIG DAVMAVYGAP LDNPDHALDA VRTARAMQVG LALLNTGWQT RGLHTLKMGI
GIHTGLVFAG NVGSPNRMKY TVVGDAVNVA ARVEGLNKEL HTTLLITTDT YAAVKDYVEV
KDCGELTVKG RHQAVKVYEV LALAEAATGS QRRRRWGRDG GSSWAVFRFW HRRAPTPPPK
PESLSPS
//
