ID   A0A1F4ZY22_9BACT        Unreviewed;       323 AA.
AC   A0A1F4ZY22;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Saccharopine dehydrogenase {ECO:0000313|EMBL:OGD11231.1};
DE   Flags: Fragment;
GN   ORFNames=A2Y86_08525 {ECO:0000313|EMBL:OGD11231.1};
OS   Candidatus Aminicenantes bacterium RBG_13_62_12.
OC   Bacteria; Candidatus Aminicenantes.
OX   NCBI_TaxID=1797269 {ECO:0000313|EMBL:OGD11231.1, ECO:0000313|Proteomes:UP000178836};
RN   [1] {ECO:0000313|EMBL:OGD11231.1, ECO:0000313|Proteomes:UP000178836}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=27774985; DOI=10.1038/ncomms13219;
RA   Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA   Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA   Williams K.H., Hubbard S.S., Banfield J.F.;
RT   "Thousands of microbial genomes shed light on interconnected biogeochemical
RT   processes in an aquifer system.";
RL   Nat. Commun. 7:13219-13219(2016).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OGD11231.1}.
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DR   EMBL; MEXX01000039; OGD11231.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1F4ZY22; -.
DR   STRING; 1797269.A2Y86_08525; -.
DR   Proteomes; UP000178836; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR032095; Sacchrp_dh-like_C.
DR   InterPro; IPR005097; Sacchrp_dh_NADP.
DR   PANTHER; PTHR11133; SACCHAROPINE DEHYDROGENASE; 1.
DR   PANTHER; PTHR11133:SF22; SACCHAROPINE DEHYDROGENASE [NADP(+), L-GLUTAMATE-FORMING]-RELATED; 1.
DR   Pfam; PF16653; Sacchrp_dh_C; 1.
DR   Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR   SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..323
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5009516225"
FT   DOMAIN          4..115
FT                   /note="Saccharopine dehydrogenase NADP binding"
FT                   /evidence="ECO:0000259|Pfam:PF03435"
FT   DOMAIN          119..323
FT                   /note="Saccharopine dehydrogenase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16653"
FT   NON_TER         323
FT                   /evidence="ECO:0000313|EMBL:OGD11231.1"
SQ   SEQUENCE   323 AA;  35560 MW;  9BD7CF9C44DA2379 CRC64;
     MKKIVVLGSG MVGRVMAADL AADFEVTAVD VSPANLDGLK KTPVKRLRAD LSDAAAVRDV
     VRGCDLVVGA VPGSMGFATL REVVAAGKDI VDISFFPEDS FLLDDAARKA GVTAVVDCGV
     APGMSNMILG YHAARMSVER FECYVGGLPF QREFPFEYKA PFSPADVIEE YTRPARYVEN
     GHVVVKPALS DVENMDFPEI GTLEAFNSDG LRSLLATMKV PNMIEKTLRY PGHAGHIRAL
     RDSGFFGGEE IEVRGRRVRP LDVTSAVLFK HWRLHEEDDE FTIMRIIVEG EENGRPKRYT
     YGLFDRRDRT TGFSSMARTT GFP
//