ID A0A1F5A4E0_9BACT Unreviewed; 862 AA.
AC A0A1F5A4E0;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=Zinc-hook domain-containing protein {ECO:0000259|PROSITE:PS51131};
GN ORFNames=A2V47_06880 {ECO:0000313|EMBL:OGD13423.1};
OS Candidatus Atribacteria bacterium RBG_19FT_COMBO_35_14.
OC Bacteria; Atribacterota.
OX NCBI_TaxID=1797291 {ECO:0000313|EMBL:OGD13423.1, ECO:0000313|Proteomes:UP000177701};
RN [1] {ECO:0000313|EMBL:OGD13423.1, ECO:0000313|Proteomes:UP000177701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the SMC family. RAD50 subfamily.
CC {ECO:0000256|ARBA:ARBA00009439}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGD13423.1}.
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DR EMBL; MEYH01000111; OGD13423.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F5A4E0; -.
DR STRING; 1797291.A2V47_06880; -.
DR Proteomes; UP000177701; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006302; P:double-strand break repair; IEA:InterPro.
DR Gene3D; 1.10.287.510; Helix hairpin bin; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038729; Rad50/SbcC_AAA.
DR InterPro; IPR013134; Zn_hook_RAD50.
DR PANTHER; PTHR32114; ABC TRANSPORTER ABCH.3; 1.
DR PANTHER; PTHR32114:SF2; ABC TRANSPORTER ABCH.3; 1.
DR Pfam; PF13476; AAA_23; 1.
DR Pfam; PF13558; SbcC_Walker_B; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF75712; Rad50 coiled-coil Zn hook; 1.
DR PROSITE; PS51131; ZN_HOOK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00471}; Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00471}.
FT DOMAIN 389..487
FT /note="Zinc-hook"
FT /evidence="ECO:0000259|PROSITE:PS51131"
FT COILED 213..278
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 323..430
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 455..485
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 513..560
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 584..625
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 667..694
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 435
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00471"
FT BINDING 438
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00471"
SQ SEQUENCE 862 AA; 100734 MW; 0FE0EA843E69CB5C CRC64;
MIPVTLALKN FLSYGEDVPP LDFSQFHIAC LSGNNGQGKS ALLDALTWAV WGEGRKASQE
KKADNSLLRI GQKDMQVEFV FDLEGDRYRV IRNYSLAQKS SRSSLEFQVF SQEDNEYISL
TGPSIRETQE RITKTLRIDY HTFINSAFIL QGRIDEFSRK SARERKEILS EILGLSRYDE
LANLAKSHLK EINNIIMTKE SRLAYIYQET ANLDFYKEKI KELSESYQDI SRKIKTEETK
VGKLKEEINL LKHKSEQYAE LEGRIVQYKQ EIARGQKQIE LRKKEIIDYE KIISQKEKVL
NDFKNYQKFN TENNEFSRKL QRIRKIEEEK ILTERRIESE RADLEVKVRN KKDRYKDLEN
RAEQGAKNKV KVLELEKKMK EIKSLEEQSE KIRQKGSELN VKINSIEGQI EKLEKDHKDN
QEKLRLLREN PEGECPLCEA RLNAERKRKI EDSINKEISL NLKQIEKSRK ETEELSKQKD
KLAETWKETN QRLKDKDIWQ KKLSKGHFEY EESTQAAKLM VGLQEEIKKL EKTIQEKKYA
SEEQKILKEL EEQIKNIDYN EKKHCQLNGK IEELRNAPLE KAKLEEAGKK IDSLRDGLSE
LQENYQQKEL DLKDLAKKRE KVKIELKELP SLKEKLVQEE QALKSDQILK DKILEERGGY
QSKFDQCLKL EKERKEISKE LEKSRKEQNI YEKLIIAFGK NGIQALIIEN ALPEIEEEAN
ELLAKLTNNS TQISIESLRD LKNGGIKETL DIKISDELGI RDYEMYSGGE AFRIDFSLRI
ALSKLLTRRA GTKLRTLVID EGFGTQDEEG IDNLVQAIQS ISEDFDKILV ITHLESLRDA
FPVRIEVTKL PEIGSRFEII KN
//
