ID A0A1F5C4W0_9BACT Unreviewed; 334 AA.
AC A0A1F5C4W0;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Radical SAM protein {ECO:0000313|EMBL:OGD37905.1};
GN ORFNames=A2V45_05105 {ECO:0000313|EMBL:OGD37905.1};
OS Candidatus Aminicenantes bacterium RBG_19FT_COMBO_58_17.
OC Bacteria; Candidatus Aminicenantes.
OX NCBI_TaxID=1797275 {ECO:0000313|EMBL:OGD37905.1, ECO:0000313|Proteomes:UP000178644};
RN [1] {ECO:0000313|EMBL:OGD37905.1, ECO:0000313|Proteomes:UP000178644}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGD37905.1}.
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DR EMBL; MEYD01000093; OGD37905.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F5C4W0; -.
DR STRING; 1797275.A2V45_05105; -.
DR Proteomes; UP000178644; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd21109; SPASM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR007197; rSAM.
DR PANTHER; PTHR11228:SF7; PQQA PEPTIDE CYCLASE; 1.
DR PANTHER; PTHR11228; RADICAL SAM DOMAIN PROTEIN; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF13186; SPASM; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SFLD; SFLDG01067; SPASM/twitch_domain_containing; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 15..165
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|Pfam:PF04055"
FT DOMAIN 239..300
FT /note="4Fe4S-binding SPASM"
FT /evidence="ECO:0000259|Pfam:PF13186"
SQ SEQUENCE 334 AA; 38734 MW; 20359383E08EA1AC CRC64;
MGKPWKWTVD MEAAVITTYR CIQKCAMCRT WKFPTTEEEE FRPSLLEKLP RLSFCNITGG
EPFLREDLSD IVAILKRKAK RIVISTNGYL TEKILRLAGE HRDVGIRVSL EGLAAVNDKL
RGMSGSFDRG LQTVQELKRM KMKDIGFAMT VSDTNPGDLL DLFHLAQGLG VELATAVVHN
SFYFHTSDNE LKNKEEILRN FQQLVRELLR SGKMKNWYRA YFNFGLMEYV QGHPRLLPCP
AGTDVFFLDP WGEVYPCNGL EKRFWLESLG NLHRQTFQQI WHSRRAEDIR AKANRCPKNC
WMIGTASPAM KRNIWRPTLW ILQNKIFPHQ QHTP
//
