ID A0A1F5CN66_9ARCH Unreviewed; 452 AA.
AC A0A1F5CN66;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=Cation efflux protein cytoplasmic domain-containing protein {ECO:0000259|Pfam:PF16916};
GN ORFNames=A3K79_07300 {ECO:0000313|EMBL:OGD44296.1};
OS Candidatus Bathyarchaeota archaeon RBG_13_46_16b.
OC Archaea; Candidatus Bathyarchaeota.
OX NCBI_TaxID=1797378 {ECO:0000313|EMBL:OGD44296.1, ECO:0000313|Proteomes:UP000176481};
RN [1] {ECO:0000313|EMBL:OGD44296.1, ECO:0000313|Proteomes:UP000176481}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGD44296.1}.
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DR EMBL; MEZE01000084; OGD44296.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F5CN66; -.
DR Proteomes; UP000176481; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1510.10; Cation efflux protein transmembrane domain; 1.
DR Gene3D; 3.30.70.1350; Cation efflux protein, cytoplasmic domain; 3.
DR InterPro; IPR002524; Cation_efflux.
DR InterPro; IPR027470; Cation_efflux_CTD.
DR InterPro; IPR036837; Cation_efflux_CTD_sf.
DR InterPro; IPR027469; Cation_efflux_TMD_sf.
DR NCBIfam; TIGR01297; CDF; 1.
DR PANTHER; PTHR43840; MITOCHONDRIAL METAL TRANSPORTER 1-RELATED; 1.
DR PANTHER; PTHR43840:SF15; MITOCHONDRIAL METAL TRANSPORTER 1-RELATED; 1.
DR Pfam; PF01545; Cation_efflux; 1.
DR Pfam; PF16916; ZT_dimer; 3.
DR SUPFAM; SSF160240; Cation efflux protein cytoplasmic domain-like; 3.
DR SUPFAM; SSF161111; Cation efflux protein transmembrane domain-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 81..102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 114..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 209..284
FT /note="Cation efflux protein cytoplasmic"
FT /evidence="ECO:0000259|Pfam:PF16916"
FT DOMAIN 291..363
FT /note="Cation efflux protein cytoplasmic"
FT /evidence="ECO:0000259|Pfam:PF16916"
FT DOMAIN 388..451
FT /note="Cation efflux protein cytoplasmic"
FT /evidence="ECO:0000259|Pfam:PF16916"
SQ SEQUENCE 452 AA; 50155 MW; 14A2999F6E1C03F1 CRC64;
MESGYRLRTL KLSTIAISSV VLVEVSLGLT AGSLAIVSDG LHALLDALTT FMLFFVTRAS
LKPPDEEHMY GHEKFEPIGG LIGGIALIGI ALTILYEAIL KILSNQAINM ELEYVGFIAI
GFTFCIDFFR VGIFSRARKS ESSTMKAGLY HAIADLSSTV IAFVGFGLAA LGINAGDALA
SVVLSILLSY LSVRLVWSSG MELSDTISKD VADRVREEIL TTKVVCKCED LKIRKAGDKT
YVRVTVQVPD YLGLEEAHDL TSQIEANIKK VVGNAEVAIH TEPCETEMPT ERLVEKLATE
VQGVKEAHEI NTSYTDGKLY ITLHAYVDPK LSVEEAHKIA ERIEDRIEAK VANLENVAVH
VEPFSPKKQR GSMVDENEII KVVYGVGRNH QRTFRIKRIV TYVADKKRYI NIDCCFVKEM
SIEEAHEVTS QIEETLRERF EETIVVVHME PN
//
