ID A0A1F5CRR2_9ARCH Unreviewed; 441 AA.
AC A0A1F5CRR2;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Macrolide transporter {ECO:0000313|EMBL:OGD45543.1};
GN ORFNames=A3K79_00060 {ECO:0000313|EMBL:OGD45543.1};
OS Candidatus Bathyarchaeota archaeon RBG_13_46_16b.
OC Archaea; Candidatus Bathyarchaeota.
OX NCBI_TaxID=1797378 {ECO:0000313|EMBL:OGD45543.1, ECO:0000313|Proteomes:UP000176481};
RN [1] {ECO:0000313|EMBL:OGD45543.1, ECO:0000313|Proteomes:UP000176481}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGD45543.1}.
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DR EMBL; MEZE01000055; OGD45543.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F5CRR2; -.
DR Proteomes; UP000176481; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd06173; MFS_MefA_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23513; INTEGRAL MEMBRANE EFFLUX PROTEIN-RELATED; 1.
DR PANTHER; PTHR23513:SF6; MULTIDRUG EFFLUX PUMP TAP; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 36..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 280..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 305..325
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 346..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 394..415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..185
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 441 AA; 47279 MW; 746F15043E15B655 CRC64;
MLAFTIIWIG QMFSLLGTAM TQFALTIWAW ELTGQATALA LVGFFGLAPL VLVSPLAGAI
VDRYDRKKVM MLADLAAGLP TVVVLMLYVS GNLQIWHLYV TGAFSGTFQA FHFPAYSAAV
TMILPKKQYG RANGMLAAAQ FASTIFAPIV AALLLVLIGI PGVLMIDIFT FILAISMLFL
VHIPKPPVTE AGRKGMGSIW KESLYGFRYI HERPSLLGLL LIFFAINFIA TFSFSLLAPM
ILSRTANDQI VLGSVLSASG VGGVVGSIVL SVWGGPKRKV HGVLIGLFFE SLLGMLLFGL
GRESIVWAVF SFSAMLILPI INGSSQAIWQ AKVAPDVQGR VFSTRLLIAQ ISAPAAMLMT
GPLADRFFEP AMMPGGVLAN VFGMFVGTGK GSGMALMFVI TGVLGMLISL AGYAFRVVRD
AEKILSDYDS GPSSRLEKKT E
//
