ID A0A1F5DXS1_9BACT Unreviewed; 461 AA.
AC A0A1F5DXS1;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Aldehyde dehydrogenase {ECO:0000256|PIRNR:PIRNR036492};
GN ORFNames=A3I57_03940 {ECO:0000313|EMBL:OGD59948.1};
OS Candidatus Beckwithbacteria bacterium RIFCSPLOWO2_02_FULL_47_23.
OC Bacteria; Candidatus Beckwithbacteria.
OX NCBI_TaxID=1797463 {ECO:0000313|EMBL:OGD59948.1, ECO:0000313|Proteomes:UP000176364};
RN [1] {ECO:0000313|EMBL:OGD59948.1, ECO:0000313|Proteomes:UP000176364}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|PIRNR:PIRNR036492}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGD59948.1}.
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DR EMBL; MEZQ01000032; OGD59948.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F5DXS1; -.
DR Proteomes; UP000176364; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0006081; P:cellular aldehyde metabolic process; IEA:InterPro.
DR CDD; cd07078; ALDH; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR012394; Aldehyde_DH_NAD(P).
DR PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR PIRSF; PIRSF036492; ALDH; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|PIRNR:PIRNR036492}.
FT DOMAIN 4..454
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 229
FT /evidence="ECO:0000256|PIRSR:PIRSR036492-1"
FT ACT_SITE 263
FT /evidence="ECO:0000256|PIRSR:PIRSR036492-1"
SQ SEQUENCE 461 AA; 49773 MW; 3D1DB0973E49E12B CRC64;
MPELKSINPT DGSVLGSVKI STKADIEIVV KTARQGYSQW RQVPIQKRAQ TLLKLSSLLK
QQVKPLAELI TKEMGKPITQ STDEILTTAA DLLYNAKAGP KYLTAEILAK KNKLTSVLAY
DPVGIVAAIK PWNYPINTPM LSIAPALVAG NSVIFKPSEY TSLVGKELAK LVWQAGIPKD
VFQIIYGGSR IGAMLIDQPI DMVTFTGSSA VGKEIANKCA AKLIKFSLEM GGSTPAIVCR
DADLELAAGL IVKSRFENCG QVCNAVKRVF VERAVASKLT NLIVKKTKAL KVGNPMDPAT
DVGPLVSAKQ LAAFENQITR GVVQGGRILT GGRRIREGKF MAGNFHQPTV MIHVQPRIDI
MSEETFGPVL PICDVDNLDQ AIHYANLSPY GLTSAGFTKS KASAERIANE VVAGGCYINK
DVAFYPGSPW TGLKDSGFGT AGGKHGLWEF THKRHLHFEQ V
//
