ID A0A1F5GA23_9BACT Unreviewed; 700 AA.
AC A0A1F5GA23;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=FtsK domain-containing protein {ECO:0000259|PROSITE:PS50901};
GN ORFNames=A3D04_04210 {ECO:0000313|EMBL:OGD88732.1};
OS Candidatus Curtissbacteria bacterium RIFCSPHIGHO2_02_FULL_40_16b.
OC Bacteria; Candidatus Curtissbacteria.
OX NCBI_TaxID=1797714 {ECO:0000313|EMBL:OGD88732.1, ECO:0000313|Proteomes:UP000177369};
RN [1] {ECO:0000313|EMBL:OGD88732.1, ECO:0000313|Proteomes:UP000177369}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SIMILARITY: Belongs to the FtsK/SpoIIIE/SftA family.
CC {ECO:0000256|ARBA:ARBA00006474}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGD88732.1}.
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DR EMBL; MFBD01000018; OGD88732.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F5GA23; -.
DR STRING; 1797714.A3D04_04210; -.
DR Proteomes; UP000177369; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 3.30.980.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041027; FtsK_alpha.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR018541; Ftsk_gamma.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22683:SF41; DNA TRANSLOCASE FTSK; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR Pfam; PF17854; FtsK_alpha; 1.
DR Pfam; PF09397; FtsK_gamma; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00843; Ftsk_gamma; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 50..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 83..102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 122..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 354..541
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT BINDING 371..378
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 700 AA; 76103 MW; 17A891ABF542417E CRC64;
MPRRRTKVAP IQLEKKTIIT IVGFSLVGFS ILLFLSFFTN AAALTSLRGY FYKLFGLGTI
IIPLLIIISA LPLLSVKLRV AKLNIILGAF STMLSLLALI SPLRASLAGN LPSALWSVMS
SLVTPVGAFF VLFFIFIIST FITLNTSLEN AISAIVGSYK KITNFFKSVK LKIFGPPKPK
FVTKGAPIFQ KAHIRDTDGP AGLKDNIVVN TPGEAKVWQY PPLSLLSQSR GAQANRGNLK
QNAQVIEKTL ESFGITAKVV EVNLGPTVTQ YALQIPMGTK LSKILTLQND LALALATLTG
NVRIEAPIPG KSQVGIEIPN ISPEIVSLKN ILSNDQMRSS KSKLTVGLGL DVSGSPVITD
IAKMPHVLIA GTTGSGKSVL MNTIIATILF RASPQEVKFI MVDPKRVELT DYNDIPHLLT
PVIVEPEKIL SALKWTMAEM DRRYKLFNKA QVRNIASYNE LSGFQALPHI VLVVDELQNL
MEFAPVEVED TIVRLAAMAR ATGIHLVVAT QRPSVDVITG LIKANIPCRI AFNVSSMVDS
RVIIDQPGAE KLLGKGDMLF VPPDASKPSR IQGVYVSDTE IRNLISFLKK SGVEPEYTEE
VITMPLGKMK GGAGGAEGER DELFEEAIRT VCQYDRASAS LLQRRLKIGY ARAARILDEL
ETAGVVGQGE GSKPRDVLVK NPEDFFQAHA EAQNPPQESA
//
