ID A0A1F5L046_9EURO Unreviewed; 1349 AA.
AC A0A1F5L046;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Reverse transcriptase {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=PENARI_c180G01925 {ECO:0000313|EMBL:OGE46582.1};
OS Penicillium arizonense.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=1835702 {ECO:0000313|EMBL:OGE46582.1, ECO:0000313|Proteomes:UP000177622};
RN [1] {ECO:0000313|EMBL:OGE46582.1, ECO:0000313|Proteomes:UP000177622}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 141311 {ECO:0000313|EMBL:OGE46582.1,
RC ECO:0000313|Proteomes:UP000177622};
RX PubMed=27739446; DOI=10.1038/srep35112;
RA Grijseels S., Nielsen J.C., Randelovic M., Nielsen J., Nielsen K.F.,
RA Workman M., Frisvad J.C.;
RT "Penicillium arizonense, a new, genome sequenced fungal species, reveals a
RT high chemical diversity in secreted metabolites.";
RL Sci. Rep. 6:35112-35112(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGE46582.1}.
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DR EMBL; LXJU01000180; OGE46582.1; -; Genomic_DNA.
DR STRING; 1835702.A0A1F5L046; -.
DR OrthoDB; 2202746at2759; -.
DR Proteomes; UP000177622; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR CDD; cd09276; Rnase_HI_RT_non_LTR; 1.
DR CDD; cd01650; RT_nLTR_like; 1.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR PANTHER; PTHR33481; REVERSE TRANSCRIPTASE; 1.
DR PANTHER; PTHR33481:SF1; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF14529; Exo_endo_phos_2; 1.
DR Pfam; PF00075; RNase_H; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50879; RNASE_H_1; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000177622}.
FT DOMAIN 642..898
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT DOMAIN 1114..1260
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|PROSITE:PS50879"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:OGE46582.1"
FT NON_TER 1349
FT /evidence="ECO:0000313|EMBL:OGE46582.1"
SQ SEQUENCE 1349 AA; 152409 MW; 0633DBCFA496F50D CRC64;
SGSAEAARNN TEWLNELGNN TKLVKPRFGI VVHRTPTENF DLENANSQAI QRIMEENDLA
DKGFQIEELA WLKRKDKVLG KFASLGIWFD SAEGAEYILN NGLLVGQRYI GSHGRARKHH
AVDIVQVNTS GNDAPQGSGL DAWIVAANTQ LVTDSLNIMK SGPRMEALIN DHQTQNLDVL
LIQEPSITTY QTHVNHSAWR LYRPTLETDA DRFRSLIYVN QRISTSSHRQ ILCDHPDIAA
VKIWTADTQL LLFSIYIPSV PLCTPDDASP GPAFTAIQNT ITAALRDGRR STSVVPAGDF
NRHHPTWGGN HIQPRLIEEA SDLITFFQAN GLYSCLPRGT ATYWALNDPG RNSTIDQTVT
NRPDLLIKCH LYHDNYGSDH RATYSEWNLK AQCRPATKVR KAFDRAEWNK IGQEVLRQIG
PWKEIKTRPA LDEIVQKLIE ATNAAVDRYT LDVRPTPYSK RWFTPDLKVQ QTKANQLRRK
WQESCAQIGR EHSSSITLFR EMQEKRRAWT RTIEKAKASH WRQFLDEAGE GKLWKAATYM
KPRDAWGCTP ALQVGTCELT GNEEKAQAFL DSFFPEMNTP CDSLPTLTPL ELPWQPITEL
EIQRSLKAAK GTTAPGDDNL PMLVWKQLWV YLKGIITNIF NACMTLGYHP KQWRNAKIVV
LRKHGKPDYS VPGAYRPISL LNTLGKLLEA VVARRLSYLT EKHGLLPDTQ FGGRPGRTTE
QALLVLLNAI DRAWYKNKVV TLVSFDLKGA FNGVNQTSLD ACLRARRIPA VARKWIASFM
SDRYASIGFD DFRTELAPLA NAGLAQGSPL SPILFTFFNS DLVDQPVTFH GGASAFIDDY
FRWRVGRSTE ENLAKIQSED IPRIETWARR TGSCFAAEKT ELIHLTRKRG EHLQGHIIVN
GTTVKPSPIT KLLGVIFDQE LRWKEHVQQA TKRATKVTIA LNGLRHLRPE QMRQLYQACV
TPVVDYASTV WHDPLRDKTH LRQLNTIQRT SLIRILSAFR TVATTTLEVE AHVLPTHLRL
RHRAQRTIAS LHTLPRDHPI WSALSRAQKR RDNIGSYARF PLAEAMKTMN IERLNELEII
DPRPLPPWRL DPFAEIEIGS DRETAAQKAE TTRSTSDVVV YSDASGRQDY LGAAAVALDN
NQEILEAQQV QVGPMSRWSV HVAELIGIFY AISVVFKIAH QHLRTADRQL TATILCDSRS
ALQAVQSARN RSGQRIVHAI LQAGAEVLAA GIALRLQWLP GHCDNPGNDA ADRLAKDAAS
PGKTHPFRPL LTRERAFIRR NIYSQWEQEW KSSTKGGHLR KIDNTLPASY TRRLYGNLPR
NRAYLLTQLR TGHNWLSSYR KSVGYSDDD
//
