ID A0A1F5L175_9EURO Unreviewed; 696 AA.
AC A0A1F5L175;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=EF-hand domain-containing protein {ECO:0000259|PROSITE:PS50222};
DE Flags: Fragment;
GN ORFNames=PENARI_c106G10859 {ECO:0000313|EMBL:OGE46806.1};
OS Penicillium arizonense.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=1835702 {ECO:0000313|EMBL:OGE46806.1, ECO:0000313|Proteomes:UP000177622};
RN [1] {ECO:0000313|EMBL:OGE46806.1, ECO:0000313|Proteomes:UP000177622}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 141311 {ECO:0000313|EMBL:OGE46806.1,
RC ECO:0000313|Proteomes:UP000177622};
RX PubMed=27739446; DOI=10.1038/srep35112;
RA Grijseels S., Nielsen J.C., Randelovic M., Nielsen J., Nielsen K.F.,
RA Workman M., Frisvad J.C.;
RT "Penicillium arizonense, a new, genome sequenced fungal species, reveals a
RT high chemical diversity in secreted metabolites.";
RL Sci. Rep. 6:35112-35112(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGE46806.1}.
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DR EMBL; LXJU01000106; OGE46806.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F5L175; -.
DR OrthoDB; 1362946at2759; -.
DR Proteomes; UP000177622; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR016688; MscS-like_plants/fungi.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR PANTHER; PTHR31323:SF15; MECHANOSENSITIVE ION CHANNEL PROTEIN MSY1; 1.
DR PANTHER; PTHR31323; MECHANOSENSITIVE ION CHANNEL PROTEIN MSY2; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR PIRSF; PIRSF017209; Memb_At2g17000_prd; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000177622};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 145..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 488..513
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 519..543
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 432..467
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 73..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 73..88
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 696
FT /evidence="ECO:0000313|EMBL:OGE46806.1"
SQ SEQUENCE 696 AA; 78970 MW; 5F0967A4A19B6C8D CRC64;
MDENESFHLQ EKKGDRSSSG GTYVGEPGVE SHDHLKVDTS VNYEAGQAAM STASLRRGQA
VRLEDDLQLM EAERMVSRST ETRSQHRRSS MSRTRSYPSQ RVDEFDEATN PLHEKAAVYQ
PPESPTTKLS AFVKKVHNSS FTVRYLTYIV PVVLLLLIPL LIGALNYTDT SVGGVKLMWF
SIWLEIVWLT LWAARVVGKC IPPAVSIISS IFTNNAKKWR DMAKQLEVHF VLFFWWLAVE
ISILPTMKNH HVDGDKRTRG WERTLNKLII VGLVWTILNV IEKIIIQLIA ITFHQRTYDD
RIQLNKFQIG SLTKLYQFSR ARIAEDDETF EQNPNLGTPQ STKNPLQYAS KAGRVAQRAM
KNVGNKVGDV AEGVLADFTG RQTKNSSDPY QVVLALLRTT SGCQVLARRL YRTFARDGFD
TVFSGDLKEA YDDNEEAEAA FSMFDRDMNG DISMEELEGV CVDIGRERKS ITASLKDLDS
VVSKLDQVFM FFVFIIIIIV FLTLISTSAA GVLTSAGSTI LALSWMFSTT ATEFLQSIIF
VFVKHPFDVG DRVTIYGNSG ASGLGDDYFV KEIALLYTEF KKMEGHIVQA PNSVLNNLFI
LNQRRTGALA EALPIVIKYG TTVDQMERLR HRLVEFVRSE RRDFQSMILH ELREVTENLS
LTLNVVFFYK SNWQNEGLRL QRRNKFLCML MIALQE
//
