ID A0A1F5L736_9EURO Unreviewed; 371 AA.
AC A0A1F5L736;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=O-methyltransferase domain-containing protein {ECO:0000259|Pfam:PF00891};
GN ORFNames=PENARI_c024G08983 {ECO:0000313|EMBL:OGE49044.1};
OS Penicillium arizonense.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=1835702 {ECO:0000313|EMBL:OGE49044.1, ECO:0000313|Proteomes:UP000177622};
RN [1] {ECO:0000313|EMBL:OGE49044.1, ECO:0000313|Proteomes:UP000177622}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 141311 {ECO:0000313|EMBL:OGE49044.1,
RC ECO:0000313|Proteomes:UP000177622};
RX PubMed=27739446; DOI=10.1038/srep35112;
RA Grijseels S., Nielsen J.C., Randelovic M., Nielsen J., Nielsen K.F.,
RA Workman M., Frisvad J.C.;
RT "Penicillium arizonense, a new, genome sequenced fungal species, reveals a
RT high chemical diversity in secreted metabolites.";
RL Sci. Rep. 6:35112-35112(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGE49044.1}.
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DR EMBL; LXJU01000024; OGE49044.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F5L736; -.
DR OrthoDB; 2158293at2759; -.
DR Proteomes; UP000177622; Unassembled WGS sequence.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43712:SF18; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14240)-RELATED; 1.
DR PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR PIRSF; PIRSF005739; O-mtase; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000177622};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022603}.
FT DOMAIN 228..363
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
FT ACT_SITE 299
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ SEQUENCE 371 AA; 40273 MW; 41B562909AEEA8D8 CRC64;
MSLLTRIASL LGLSSPAPVA PPGAALAATL TVPASLGFVP VAIHFDLFDI LVSLGSPASA
EKVTTTCNAR IKARDNNEPE LSTRLASDTL YIMAGLGLVE RMDEDSFSAN AITKHMVAMP
SAQHGALHFT TEGLMAGAFL MKKLQDTNFA YPFADADGPL QYAYRLMGQP ELAAQHTYSI
METQGRMDSF NRFMVGKFFK FGTFPERVKS MGYDLDSALA MDGNPGSAAM VDIGGGRGEL
LLEVQAVYPQ LTADELIVQE FNAEIDSVPG VRLMEWNYKE SSEQPIRGAR VYSLQHILHN
LPDLDAVALL QKISKAMAPG SRILIIEYAK NLTYTSLHAS MIALYGGRER SPEEWRQIAG
LTGLKVTFEA S
//
