ID A0A1F5LAK2_9EURO Unreviewed; 517 AA.
AC A0A1F5LAK2;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN ORFNames=PENARI_c017G03124 {ECO:0000313|EMBL:OGE50258.1};
OS Penicillium arizonense.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=1835702 {ECO:0000313|EMBL:OGE50258.1, ECO:0000313|Proteomes:UP000177622};
RN [1] {ECO:0000313|EMBL:OGE50258.1, ECO:0000313|Proteomes:UP000177622}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 141311 {ECO:0000313|EMBL:OGE50258.1,
RC ECO:0000313|Proteomes:UP000177622};
RX PubMed=27739446; DOI=10.1038/srep35112;
RA Grijseels S., Nielsen J.C., Randelovic M., Nielsen J., Nielsen K.F.,
RA Workman M., Frisvad J.C.;
RT "Penicillium arizonense, a new, genome sequenced fungal species, reveals a
RT high chemical diversity in secreted metabolites.";
RL Sci. Rep. 6:35112-35112(2016).
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGE50258.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LXJU01000017; OGE50258.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F5LAK2; -.
DR STRING; 1835702.A0A1F5LAK2; -.
DR OrthoDB; 3377831at2759; -.
DR Proteomes; UP000177622; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProt.
DR GO; GO:0072330; P:monocarboxylic acid biosynthetic process; IEA:UniProt.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 2.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR InterPro; IPR019819; Carboxylesterase_B_CS.
DR PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR PANTHER; PTHR11559:SF423; CARBOXYLIC ESTER HYDROLASE; 1.
DR Pfam; PF00135; COesterase; 2.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
DR PROSITE; PS00941; CARBOXYLESTERASE_B_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW Reference proteome {ECO:0000313|Proteomes:UP000177622};
KW Signal {ECO:0000256|RuleBase:RU361235}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT CHAIN 19..517
FT /note="Carboxylic ester hydrolase"
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT /id="PRO_5009363449"
FT DOMAIN 33..365
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
FT DOMAIN 377..500
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
SQ SEQUENCE 517 AA; 55528 MW; AB1A463E0A02D854 CRC64;
MQLLAFPVLA ALALGGFAVP TLSPRSNTDS GLLVETTSGS VKGFVNHTAP DVRQFLGVPF
AEPPVGDLRF ARPQKKQHGG IIKAFSLPNS CMQQFDTSAS TIYTEYESEF LVSGGNSEDC
LYLSIWAPRL DKIQSQQGPL PVLLYIPGGG FTSGGQASMY KIPDKWVQRT QSHIVVIMNY
RVNVFGFPNA KGLEDQNVGL LDQRLAVEWV YANIGNFGGD PKRITLWGQS AGAGSVAVYP
YGYPDDPLVA GLIADSGGPG IVSGSDVAHT NFTFLAGLVG CKGLSPEKEL SCVRKVPAQT
LENALSYYSG NDTLPSISFK PVIDNKTAFS NWTERVLDGK IAKTPMIIGS NSNEGAGFVS
FTPEGPGEQA LAGATKIISC PVASEAKNRH LGDLPTYRYE YAGNFSNISP LPWFGAYHSS
ELPLLFGTHS EYGGASTKFE WEVSYAMEAL WLSFAEDPTR GTVRAALGNV AANPTQQSYF
SWPQFKQGSA DMVLFAKDNK LVQLVSSKSI DTSCSVS
//
