ID   A0A1F5NVI3_9BACT        Unreviewed;       918 AA.
AC   A0A1F5NVI3;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   13-SEP-2023, entry version 15.
DE   RecName: Full=Lecithin:cholesterol acyltransferase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=A2720_02095 {ECO:0000313|EMBL:OGE81686.1};
OS   Candidatus Doudnabacteria bacterium RIFCSPHIGHO2_01_FULL_46_24.
OC   Bacteria; Candidatus Doudnabacteria.
OX   NCBI_TaxID=1817825 {ECO:0000313|EMBL:OGE81686.1, ECO:0000313|Proteomes:UP000178892};
RN   [1] {ECO:0000313|EMBL:OGE81686.1, ECO:0000313|Proteomes:UP000178892}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=27774985; DOI=10.1038/ncomms13219;
RA   Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA   Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA   Williams K.H., Hubbard S.S., Banfield J.F.;
RT   "Thousands of microbial genomes shed light on interconnected biogeochemical
RT   processes in an aquifer system.";
RL   Nat. Commun. 7:13219-13219(2016).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OGE81686.1}.
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DR   EMBL; MFEL01000006; OGE81686.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1F5NVI3; -.
DR   STRING; 1817825.A2720_02095; -.
DR   Proteomes; UP000178892; Unassembled WGS sequence.
DR   GO; GO:0008374; F:O-acyltransferase activity; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   Gene3D; 3.30.1920.20; -; 1.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR003386; LACT/PDAT_acylTrfase.
DR   PANTHER; PTHR11440:SF97; BCDNA.GH02384; 1.
DR   PANTHER; PTHR11440; LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED; 1.
DR   Pfam; PF02450; LCAT; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   4: Predicted;
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           29..918
FT                   /note="Lecithin:cholesterol acyltransferase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5009520217"
FT   REGION          177..211
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   918 AA;  101435 MW;  79B7EB84CF002840 CRC64;
     MFSDIRKAFF VLTFALVFGA IFVFPNHAAA TVTLPTTSCD TQWAELNHIG DSESAEDGTK
     AFKFGPNNND FVSETGEVVT FKPQLLFTPD ATAIFKVYVL NSSCAVIYGD SSPAIQAGLN
     TITYTKATDQ LQFNSEESSS IHWLPGYLIG FDVWDGVNGS TFDTYTYLID MDSLANPAAD
     PIPEPEPEGA APPPSFFETK KQNPEDLPEP EGLRPILIIP GITGSELYEN GELVWPPGKL
     GTAFNAKDKF LTNSLALDEK GNSVKNVISG DIIRKINFPT PFFDVNIFDA LISDLKNNNY
     ISGENYFIFP YDWRLDFDKN IELLDKIINK NKKGFHKIDI VAHSMGGLLV KDYINKKGSD
     QINKLIFVGT PHLGAPKAAK VLLEGDIDIP LNLLNKETMK QLSLNMPSIY QLLPNRKYFE
     LFTGYINLSA ERWQTPYMLD YDWTRDFLKN KNVNTYLLDQ AQEAQALSEL DLSGIDVYNI
     TGCGTNTQAG YRFTSIVSPI AGIGYTSGDQ TVPFMSARQV NTASDKKFYV KGVKHSELPS
     GSRALILDIL QNNKPALDEI STSNGTHICD YKGKSLTWKS PVEVHIYDQN NNHAGPTSEG
     GFENNLNIID YEIIDGIKFI FIPTDDSNTY SIQAKGEAAG VFDLIISDIS NGEVTSSQVF
     NDVAITEASK IAVDLYQNKV KFDYSGSGHA IELKPDSTLA EGSDDLVPPQ TFIETAGNEE
     ITIKLTASDS KSGSGILHTK YSINGKPYET YTEPVMLEEF GSVVFKYYSV DKAGNNEPVN
     ERQFNIEYNP GKVLGTSTGL KDGTLVLDSV DNRTVYIVGT GGKKYGFISE EVFKGLGYNF
     DNLVSADISD YELGGYVYTV NGPHPDGSLV RDDSGAVWVI NFGKRFGFSS EELSKSFEMN
     NIIKANWYDL NLPFERIE
//