ID A0A1F5XG04_9BACT Unreviewed; 408 AA.
AC A0A1F5XG04;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=Serine--tRNA ligase {ECO:0000256|ARBA:ARBA00039158};
DE EC=6.1.1.11 {ECO:0000256|ARBA:ARBA00012840};
DE AltName: Full=Seryl-tRNA synthetase {ECO:0000256|ARBA:ARBA00031113};
DE AltName: Full=Seryl-tRNA(Ser/Sec) synthetase {ECO:0000256|ARBA:ARBA00033352};
GN ORFNames=A3B19_02220 {ECO:0000313|EMBL:OGF86863.1};
OS Candidatus Giovannonibacteria bacterium RIFCSPLOWO2_01_FULL_46_32.
OC Bacteria; Candidatus Giovannonibacteria.
OX NCBI_TaxID=1798353 {ECO:0000313|EMBL:OGF86863.1, ECO:0000313|Proteomes:UP000177346};
RN [1] {ECO:0000313|EMBL:OGF86863.1, ECO:0000313|Proteomes:UP000177346}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- PATHWAY: Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec)
CC biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.
CC {ECO:0000256|ARBA:ARBA00005045}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGF86863.1}.
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DR EMBL; MFIF01000010; OGF86863.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F5XG04; -.
DR Proteomes; UP000177346; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004828; F:serine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00770; SerRS_core; 1.
DR Gene3D; 1.10.287.40; Serine-tRNA synthetase, tRNA binding domain; 1.
DR InterPro; IPR002314; aa-tRNA-synt_IIb.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR002317; Ser-tRNA-ligase_type_1.
DR InterPro; IPR015866; Ser-tRNA-synth_1_N.
DR InterPro; IPR042103; SerRS_1_N_sf.
DR InterPro; IPR033729; SerRS_core.
DR InterPro; IPR010978; tRNA-bd_arm.
DR NCBIfam; TIGR00414; serS; 1.
DR PANTHER; PTHR43697:SF1; SERINE--TRNA LIGASE; 1.
DR PANTHER; PTHR43697; SERYL-TRNA SYNTHETASE; 1.
DR Pfam; PF02403; Seryl_tRNA_N; 1.
DR Pfam; PF00587; tRNA-synt_2b; 1.
DR PIRSF; PIRSF001529; Ser-tRNA-synth_IIa; 1.
DR PRINTS; PR00981; TRNASYNTHSER.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR SUPFAM; SSF46589; tRNA-binding arm; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 4: Predicted;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:OGF86863.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917}.
FT DOMAIN 122..396
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
SQ SEQUENCE 408 AA; 46496 MW; 7FF9A2117228B6A2 CRC64;
MLDIKFIREN KDLIKEAARK KHVMVDIDQL SAVDEKRRAL IAEVDALRQE HKKFTGASEE
AKISKDKLSH KEFELGAVEK EFEELMLLVP NVPDPSVPEG ESDAENQEIR KWGEIKVEHG
KNYLNLMQSR GALDLERGAK VSGFRGYFLK GDAALLSMAL WQFTLDVLIK KGFAPFLAPV
LIRRENLVGT GWVGGTTPKE GEDVYKTQDD LYLSGTAEVP MMGYHADEIL KEEELPKKYV
AFSPCFRREA GSYGKDAKGI FRVHEFFKVE QVILCRADHQ ESVKWHEELT KNSEEIMQSL
EIPYRVVINC GGDLGLGQVK KYDIEAWIPS EKRYRETHSA SYFHDFQTRR LNIKYKDSAG
KIHFAHSLNN TAIATPRVLE ALLENHQEPD GSIKIPAALQ KYFGKEKI
//
