ID A0A1F5ZLJ2_9BACT Unreviewed; 292 AA.
AC A0A1F5ZLJ2;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 22-FEB-2023, entry version 16.
DE RecName: Full=Prephenate/arogenate dehydrogenase domain-containing protein {ECO:0000259|PROSITE:PS51176};
GN ORFNames=A2773_00915 {ECO:0000313|EMBL:OGG13340.1};
OS Candidatus Gottesmanbacteria bacterium RIFCSPHIGHO2_01_FULL_39_10.
OC Bacteria; Candidatus Gottesmanbacteria.
OX NCBI_TaxID=1798375 {ECO:0000313|EMBL:OGG13340.1, ECO:0000313|Proteomes:UP000177383};
RN [1] {ECO:0000313|EMBL:OGG13340.1, ECO:0000313|Proteomes:UP000177383}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGG13340.1}.
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DR EMBL; MFJE01000056; OGG13340.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F5ZLJ2; -.
DR STRING; 1798375.A2773_00915; -.
DR Proteomes; UP000177383; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR046826; PDH_N.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF20463; PDH_C; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..292
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 292 AA; 32337 MW; EF209432EA6685A4 CRC64;
MKNIHIEKVA IVGIGLIGGS IAMAMRKHLG SKVTILGLSS TSKKAQIAHK HNIIDRALTS
LKDIPQDIDL VVLSTPIVTN IKLLKSLKKL TTSKQIIIDV GSTKEMICRE AVKLDLRNFI
GTHPMAGNET SGLGNADPDL FQNKPWIICP DSQTDKSKIT FLKNFITSLG AKPFILNSKA
HDRIAALSSH IFLIMSSILV NATSKNNWDK ISQIASTGFK DTTRLASHSP NMKKEIILTN
KMNIQKALKS LSAEIELFSS LLKDDEENKI MNYFQQAKSV RDDWLNKYSI NT
//
