ID A0A1F6BLC9_9BACT Unreviewed; 490 AA.
AC A0A1F6BLC9;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=HD domain-containing protein {ECO:0000259|PROSITE:PS51831};
GN ORFNames=A2110_01555 {ECO:0000313|EMBL:OGG37729.1};
OS Candidatus Jorgensenbacteria bacterium GWA1_54_12.
OC Bacteria; Candidatus Jorgensenbacteria.
OX NCBI_TaxID=1798468 {ECO:0000313|EMBL:OGG37729.1, ECO:0000313|Proteomes:UP000176273};
RN [1] {ECO:0000313|EMBL:OGG37729.1, ECO:0000313|Proteomes:UP000176273}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the tRNA nucleotidyltransferase/poly(A)
CC polymerase family. {ECO:0000256|RuleBase:RU003953}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGG37729.1}.
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DR EMBL; MFKH01000004; OGG37729.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F6BLC9; -.
DR STRING; 1798468.A2110_01555; -.
DR Proteomes; UP000176273; Unassembled WGS sequence.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0031123; P:RNA 3'-end processing; IEA:UniProt.
DR CDD; cd00077; HDc; 1.
DR CDD; cd05398; NT_ClassII-CCAase; 1.
DR Gene3D; 1.10.246.80; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR Gene3D; 1.10.3090.10; cca-adding enzyme, domain 2; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR002646; PolA_pol_head_dom.
DR InterPro; IPR032828; PolyA_RNA-bd.
DR NCBIfam; TIGR00277; HDIG; 1.
DR PANTHER; PTHR46173; CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR46173:SF1; CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL; 1.
DR Pfam; PF01966; HD; 1.
DR Pfam; PF01743; PolyA_pol; 1.
DR Pfam; PF12627; PolyA_pol_RNAbd; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81891; Poly A polymerase C-terminal region-like; 1.
DR PROSITE; PS51831; HD; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW RNA-binding {ECO:0000256|RuleBase:RU003953};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003953}.
FT DOMAIN 255..369
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
SQ SEQUENCE 490 AA; 55506 MW; 8BEE6478E0A714CA CRC64;
MAYSLPQEVR EIVEGLHREG YGAYPVGGCV RDLVIGRAPK DWDVTTDATP EEVQKIFPES
VYENEFGTVG VKTGSDDATL TIVEVTTFRK EGRYSDKRHP DEVTFAKTID DDLSRRDFTV
NALALNVAEE QEVIDPYGGR RDLKNKVIRA VGNPAERFKE DALRLVRAPR LVTELGIAEG
WHIEDKTYAA IREHASLLRE IAVERVRDEL VRLMLGQDAA QGLRLLEELG LLQYIMPEVR
EGIGIDQAKH HTFTVWEHGI RSLQYAAERG FSLTVRMSAL LHDVGKPRTK AGEGEAATFY
NHEIVGARMT RELLTRLAFP KQFVQDVAHL VRYHLFYYNV GEVTEAGVRR FVRRAGVEYI
DDLLRLREAD RIGSGVPKAF PYKLRHLLYM IEKVRRDPLS VKALAVDGEA VMKTVGLVPG
PRVGWILNAL MEEVLDAPEK NTEELLTKRM KALAKLSDEE LQEKGEKGKR QMEEFERGVE
AEIKGKYRVG
//
