ID A0A1F6CK57_9BACT Unreviewed; 686 AA.
AC A0A1F6CK57;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=UvrABC system protein B {ECO:0000256|ARBA:ARBA00029504, ECO:0000256|RuleBase:RU003587};
GN ORFNames=A2678_00555 {ECO:0000313|EMBL:OGG49262.1};
OS Candidatus Kaiserbacteria bacterium RIFCSPHIGHO2_01_FULL_53_31.
OC Bacteria; Candidatus Kaiserbacteria.
OX NCBI_TaxID=1798481 {ECO:0000313|EMBL:OGG49262.1, ECO:0000313|Proteomes:UP000178815};
RN [1] {ECO:0000313|EMBL:OGG49262.1, ECO:0000313|Proteomes:UP000178815}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SUBUNIT: Forms a heterotetramer with UvrA during the search for
CC lesions. Interacts with UvrC in an incision complex.
CC {ECO:0000256|ARBA:ARBA00026033, ECO:0000256|RuleBase:RU003587}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|RuleBase:RU003587}.
CC -!- SIMILARITY: Belongs to the UvrB family. {ECO:0000256|ARBA:ARBA00008533,
CC ECO:0000256|RuleBase:RU003587}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGG49262.1}.
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DR EMBL; MFKU01000002; OGG49262.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F6CK57; -.
DR STRING; 1798481.A2678_00555; -.
DR Proteomes; UP000178815; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR CDD; cd17916; DEXHc_UvrB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001943; UVR_dom.
DR InterPro; IPR036876; UVR_dom_sf.
DR InterPro; IPR004807; UvrB.
DR InterPro; IPR041471; UvrB_inter.
DR InterPro; IPR024759; UvrB_YAD/RRR_dom.
DR NCBIfam; TIGR00631; uvrb; 1.
DR PANTHER; PTHR24029; UVRABC SYSTEM PROTEIN B; 1.
DR PANTHER; PTHR24029:SF0; UVRABC SYSTEM PROTEIN B; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF04851; ResIII; 1.
DR Pfam; PF02151; UVR; 1.
DR Pfam; PF12344; UvrB; 1.
DR Pfam; PF17757; UvrB_inter; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF46600; C-terminal UvrC-binding domain of UvrB; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50151; UVR; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|RuleBase:RU003587};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769,
KW ECO:0000256|RuleBase:RU003587};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|RuleBase:RU003587};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881,
KW ECO:0000256|RuleBase:RU003587};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW SOS response {ECO:0000256|RuleBase:RU003587}.
FT DOMAIN 25..202
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 448..606
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 637..672
FT /note="UVR"
FT /evidence="ECO:0000259|PROSITE:PS50151"
FT COILED 259..286
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 686 AA; 77890 MW; 679380898C1C1DD9 CRC64;
MANFKLHTPY PPAGDQPKAI EALERGLDEG MRHQTLFGVT GSGKTFTMAN VIAKFDKPTL
VLAHNKTLAA QLAQEYREFF PTNAVHYFVS YYDYYQPEAY IAHSDTYIEK EAMINAEIDR
LRHAATQALL TRRDVIIVAS VSAIYGLGSP EEYEKVHVKI EKDAKENRAA LIRKLVGIYF
ERTTADLNPG QVRAVGNSLE FMPVNESIIY HVTFAGEHIS RIEKLDPVSR AMRKPDDGDL
ASVFVFPAKH FITTEDERNR AIEDIKLELE EQLAKFKREE KPLEAERLKR RTMHDIARIR
ELGYTSGIEN YSRHFDGRKA GEPPYTLLSY FPHTKEGGAD FLTVIDESHV TVPQIGGMFA
GDRSRKDNLV EYGFRLPSAR DNRPLMFEEF EERVGQVIYT TATPGQYERA HSEQVVQQII
RPTGLIDPEL TVRPVNETVK HGGQIADFIN EAEIVIKRGG RALATTLTKQ MAEDLAQFLR
KRGMKAEYLH SDVKTIDRID ILTNFRKGVF DILVGVNLLR EGLDLPEVEL VGILDADKEG
FLRSETSLIQ TIGRAARNVL GRVILYADQM TDSLTKAIGE TNRRRALQIA YNEKHGITPK
TIKKEIHDIA ASMRTEHQRT LDELLVLDTL AYKDDPAEFI KRKRDEMAEA VEQLDFETAA
LIRDEIYKLE GTGPKVKKTH TRKIFS
//
