ID A0A1F6DWG7_9BACT Unreviewed; 561 AA.
AC A0A1F6DWG7;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein {ECO:0000259|Pfam:PF16576};
GN ORFNames=A3D71_01775 {ECO:0000313|EMBL:OGG65779.1};
OS Candidatus Kaiserbacteria bacterium RIFCSPHIGHO2_02_FULL_55_20.
OC Bacteria; Candidatus Kaiserbacteria.
OX NCBI_TaxID=1798497 {ECO:0000313|EMBL:OGG65779.1, ECO:0000313|Proteomes:UP000177652};
RN [1] {ECO:0000313|EMBL:OGG65779.1, ECO:0000313|Proteomes:UP000177652}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGG65779.1}.
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DR EMBL; MFLK01000030; OGG65779.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F6DWG7; -.
DR STRING; 1798497.A3D71_01775; -.
DR Proteomes; UP000177652; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 2.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 2.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 30..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 360..462
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 561 AA; 57638 MW; A84ECA9A84DF9849 CRC64;
MHPKMLIIKA VLLIRGGGPR ALRLASQVGW WKVGTGIAVL VLGTGAVVFI SGGSESEAAP
VIQIRSVEVK SVAELSSQTS PLSLVGSVTS QSEATVRAEK SGQVTRVNTS LGAGISVGAV
AAEIENASER AAVLQAEGGL DAAQANLAKV QGGVRDEQRS ILEANVTAAT AALESARSSA
LSTLLSAYAT MDSGILATTD KLFTNPGKTG SKFNIVTSDS RLTIEIETTR DVLTPYLARE
AAISDSLTAS SDLATEIATT QTEVRAARNF LDLIVSALNK AIPSPAASSA QIATYLAEAT
AVRTSLTSTL SALSGATQNL SASQSALDVA RKNLEQGVTG GQPEDVAAAR AAVKQAQGGL
AAARANLEKT IIRAPISGTI NSFSLKRGDY VQMTAPVLTV ANNGSLEVVT YISENNAREV
SVGQPVTIEK ASGVVTRIAP ALDPVTKKIE VRIGVNNPKG LINGQSVLVS IVRTRSVSGD
ATRITIPIAA VKVEAERTTV FTLDVNVLVA HEVTLGALLG ERVVISGGLT FDMRIVVDAR
GLREGEKVEV SAGGGSSSGG K
//
