ID A0A1F6HR76_9BACT Unreviewed; 586 AA.
AC A0A1F6HR76;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Penicillin-binding protein 2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=A2776_03225 {ECO:0000313|EMBL:OGH12827.1};
OS Candidatus Levybacteria bacterium RIFCSPHIGHO2_01_FULL_40_10.
OC Bacteria; Candidatus Levybacteria.
OX NCBI_TaxID=1798593 {ECO:0000313|EMBL:OGH12827.1, ECO:0000313|Proteomes:UP000177290};
RN [1] {ECO:0000313|EMBL:OGH12827.1, ECO:0000313|Proteomes:UP000177290}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGH12827.1}.
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DR EMBL; MFNQ01000015; OGH12827.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F6HR76; -.
DR STRING; 1798593.A2776_03225; -.
DR Proteomes; UP000177290; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 31..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 119..198
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 232..580
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 586 AA; 64406 MW; 37388F6ED64AF5F2 CRC64;
MVRIGPAFFE SISNERGARR RFHSSVVSAD LLFIAPLFLA AICFLVIGVR LFYIQIIRGE
YYTALSDQNR TRTEILLAPR GVILDRLGRP LAQNSASFKV GKGEEALTRD EALKLIQQGR
NVKITAGRDY LYKGAFAHVL GYVGPISEDE VIMPEFSGYA ISDIVGKIGL EREYEAQLHG
RNGKKLFEVD AQGKFVRELG SESPVPGQNL KTTLDRDIQL AVAVSFKDVE RGAVVVSDPR
SGAILAMFSK PTFDPNLFIL GDTYEAEGDY KTRESILSDT EGLPLLDRAI GGAYPPGSTF
KLVTATAALE KGAITPNTQI EDTGILKVGA FSFGNWYFLQ YGRTEGSLDI VGAIKRSNDI
FFYKAAEGAG VNIISDWANR FGLGKKLGID LSGEVSGTVP TTEWKEKTIG EQWYLGDTYN
YGIGQGYLLT TPLQVNMFTT VFANGGTLYQ PHLLQSQKAK VKRQNFINKK NIDLVRQGMM
ESCETGGVAW PFFNFKVKNP NLTADDRDYI RDASDSADMV RVKVACKTGT AEIGGKDDKP
HAWISVFAPF HEPEIVVTVL VENGGEGSSI AGPVARDILK DYFEKK
//
