ID A0A1F6IBR0_9BACT Unreviewed; 372 AA.
AC A0A1F6IBR0;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Ornithine decarboxylase {ECO:0008006|Google:ProtNLM};
GN ORFNames=A3D74_03805 {ECO:0000313|EMBL:OGH19993.1};
OS Candidatus Levybacteria bacterium RIFCSPHIGHO2_02_FULL_37_13.
OC Bacteria; Candidatus Levybacteria.
OX NCBI_TaxID=1798602 {ECO:0000313|EMBL:OGH19993.1, ECO:0000313|Proteomes:UP000177483};
RN [1] {ECO:0000313|EMBL:OGH19993.1, ECO:0000313|Proteomes:UP000177483}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR600183-50};
CC -!- SIMILARITY: Belongs to the Orn/Lys/Arg decarboxylase class-II family.
CC {ECO:0000256|ARBA:ARBA00008872, ECO:0000256|RuleBase:RU003737}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGH19993.1}.
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DR EMBL; MFNZ01000028; OGH19993.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F6IBR0; -.
DR STRING; 1798602.A3D74_03805; -.
DR Proteomes; UP000177483; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0006596; P:polyamine biosynthetic process; IEA:InterPro.
DR CDD; cd00622; PLPDE_III_ODC; 1.
DR Gene3D; 3.20.20.10; Alanine racemase; 1.
DR InterPro; IPR009006; Ala_racemase/Decarboxylase_C.
DR InterPro; IPR022643; De-COase2_C.
DR InterPro; IPR022644; De-COase2_N.
DR InterPro; IPR000183; Orn/DAP/Arg_de-COase.
DR InterPro; IPR002433; Orn_de-COase.
DR InterPro; IPR029066; PLP-binding_barrel.
DR PANTHER; PTHR11482; ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE; 1.
DR PANTHER; PTHR11482:SF6; ORNITHINE DECARBOXYLASE 1-RELATED; 1.
DR Pfam; PF02784; Orn_Arg_deC_N; 1.
DR Pfam; PF00278; Orn_DAP_Arg_deC; 1.
DR PRINTS; PR01179; ODADCRBXLASE.
DR PRINTS; PR01182; ORNDCRBXLASE.
DR SUPFAM; SSF50621; Alanine racemase C-terminal domain-like; 1.
DR SUPFAM; SSF51419; PLP-binding barrel; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR600183-50}.
FT DOMAIN 24..261
FT /note="Orn/DAP/Arg decarboxylase 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02784"
FT DOMAIN 262..348
FT /note="Orn/DAP/Arg decarboxylase 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00278"
FT ACT_SITE 321
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600183-50"
FT MOD_RES 47
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR600183-50"
SQ SEQUENCE 372 AA; 41575 MW; D8C0AAD47554DFA1 CRC64;
MKLNKQIINK SNQFKTPFLL VDLKQVSKHY NNIKKNLSGV EVFYSMKAND HPRIVETLVK
ENASFDITSE RELNSLNKNS LSSKKITCLN PIKSPEFLKR LFENKITIMA YDSFDEVDKI
ARYAPGSKLV LRIVVDNEGS DWPLTKKYGV NPAEALPLLK YALGKKLQPI GLTFHVGSQC
RNKNNWVNAL FVCETLWALA KKENIHFNFL SLGGGLPIQH DRPIPALEDI GKGIKKMLSN
NFKSADSPLR VAIEPGRAIV GDSAIMVTSV IGKAKRGSEN WLYVDTGVFN GFMETIDGFT
YDIKTIKNTA IKKFTIGGPS CDSVDIPFKN VVLEDVKIGD KIYVLNAGAY TTVYASTFNG
FEIPKTYFLS DD
//
