ID A0A1F6PBV0_9BACT Unreviewed; 435 AA.
AC A0A1F6PBV0;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Cation/H+ exchanger domain-containing protein {ECO:0000259|Pfam:PF00999};
GN ORFNames=A2538_04215 {ECO:0000313|EMBL:OGH93629.1};
OS Candidatus Magasanikbacteria bacterium RIFOXYD2_FULL_41_14.
OC Bacteria; Candidatus Magasanikbacteria.
OX NCBI_TaxID=1798709 {ECO:0000313|EMBL:OGH93629.1, ECO:0000313|Proteomes:UP000178254};
RN [1] {ECO:0000313|EMBL:OGH93629.1, ECO:0000313|Proteomes:UP000178254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGH93629.1}.
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DR EMBL; MFRE01000025; OGH93629.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F6PBV0; -.
DR STRING; 1798709.A2538_04215; -.
DR Proteomes; UP000178254; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR PANTHER; PTHR43562; NAPA-TYPE SODIUM/HYDROGEN ANTIPORTER; 1.
DR PANTHER; PTHR43562:SF3; SODIUM ION_PROTON EXCHANGER (EUROFUNG); 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
PE 4: Predicted;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 7..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 36..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 68..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 121..145
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..173
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 185..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 218..237
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 338..356
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 368..390
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 396..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 48..411
FT /note="Cation/H+ exchanger"
FT /evidence="ECO:0000259|Pfam:PF00999"
SQ SEQUENCE 435 AA; 46174 MW; 9DCB5342FB1F23AD CRC64;
MAKIKGIILL ILETLGAALI LFYLRKALIS SENHEVSVIL PMLIDIAFLA FFASFGGRLA
KIIHIAPMAG KIIMGIIAGP AVLGVIAPYS EGVELSRLAG VLFILFEAGL HFDMELLKKN
WLVATIIAHV GVIIPLISIG LLGHYAFGMA WMPAIFLGGV FTATSVGLSV EALKRAGKLE
TDMGNKIIGA AVIDDILGVL VLTILAKLSS EGHLEAMGIV WIIVAVVAFF GGAYILWNMG
IAQSIAKYLD THYVDSSTGP HTRFFFGALM MAGALAAVIG LEPVLGAFGI GVVLSKVDNE
IKHSTWEKIE GHMHIFVGGF LVSIGTMLPR EALLSAKAWL LAIILTIIGF VGKYLTRYLV
KDKVEGHLVG LAMSIRGEVG LVFVAVALAN HVLDDVTAAA ALLGVIIVTV IGAIWFEKAV
MKQTGVKMSE AGEAI
//
