ID A0A1F6R5M6_9ARCH Unreviewed; 670 AA.
AC A0A1F6R5M6;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=A3K63_01055 {ECO:0000313|EMBL:OGI15928.1};
OS Candidatus Micrarchaeota archaeon RBG_16_49_10.
OC Archaea; Candidatus Micrarchaeota.
OX NCBI_TaxID=1801633 {ECO:0000313|EMBL:OGI15928.1, ECO:0000313|Proteomes:UP000176807};
RN [1] {ECO:0000313|EMBL:OGI15928.1, ECO:0000313|Proteomes:UP000176807}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- SIMILARITY: Belongs to the MCM family. {ECO:0000256|ARBA:ARBA00008010,
CC ECO:0000256|RuleBase:RU004070}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGI15928.1}.
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DR EMBL; MFRS01000003; OGI15928.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F6R5M6; -.
DR Proteomes; UP000176807; Unassembled WGS sequence.
DR GO; GO:0042555; C:MCM complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR Gene3D; 2.20.28.10; -; 1.
DR Gene3D; 3.30.1640.10; mini-chromosome maintenance (MCM) complex, chain A, domain 1; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR031327; MCM.
DR InterPro; IPR008047; MCM_4.
DR InterPro; IPR001208; MCM_dom.
DR InterPro; IPR041562; MCM_lid.
DR InterPro; IPR027925; MCM_N.
DR InterPro; IPR033762; MCM_OB.
DR InterPro; IPR048907; MCM_WH.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR11630; DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER; 1.
DR PANTHER; PTHR11630:SF43; DNA REPLICATION LICENSING FACTOR MCM6; 1.
DR Pfam; PF00493; MCM; 1.
DR Pfam; PF17855; MCM_lid; 1.
DR Pfam; PF14551; MCM_N; 1.
DR Pfam; PF17207; MCM_OB; 1.
DR Pfam; PF21120; MCM_WH_arc; 1.
DR PRINTS; PR01657; MCMFAMILY.
DR PRINTS; PR01660; MCMPROTEIN4.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00350; MCM; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50051; MCM_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004070};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004070};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004070}.
FT DOMAIN 272..479
FT /note="MCM"
FT /evidence="ECO:0000259|PROSITE:PS50051"
SQ SEQUENCE 670 AA; 75700 MW; 1A8FBE4CA88E2022 CRC64;
MDKDQIINQF SEFLRQNYYK ELAKTVSKGL ESIYIDFSLI DKFNPDLSDE IIDTPEATID
YLNESIRQFD FSEKATVTVR LFNLPESTNI RIRNIRAKNI GKLLSVDGIV KRASEVRPEV
SEIVFECPEC GNRMSVIQTE KEKTMKYPAR CDCGNRRNFR VLKEKLYDAR WITIEEPFEI
TTGERPSDMM VYLTEDLVST KLRNKTEPGN RIRVVGILKE IPRRTAKGQQ TKQKDILIAA
NNVESVEIEW EELMITPEDA KRIKDLANDK GIYDKLVGSL APTMFGLEKV KMAIIFQLFG
GVPHLLQDNT RIRGDIHILL IGDPSVGKSQ LLKLATSIIP RGKYVSGKGV TGAGLTATVV
KDEQFLGGWV LEAGVLVMAN QSICAIDEFE KMEKTDQIAM HEAMSLQQIS IAKATIVATL
PSRTAILGGA NPKLGRFDPY IPIREQVDLP ETILSRFDVK FALRDVPNAE MDERIITHVL
DSRHFKKDEI KSAIEPEFLR KYIAYAKKNC KPELTREAGN ALKDFYVGLR STAGGEDSAI
PITLRQCEAL IRLAEASAKI RLSDKVTMED ADRAIDIMKF SIRQFGFDQE TGMIDIDRAE
GGTPSTQRNK MRIVLDTLNE LHQVMGKNIP MEEVVKRCRD AGVENIEEII RKMKSEGLVF
EPKPGFIQKV
//
