ID A0A1F6RM62_9BACT Unreviewed; 250 AA.
AC A0A1F6RM62;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase {ECO:0008006|Google:ProtNLM};
GN ORFNames=A2255_07405 {ECO:0000313|EMBL:OGI21741.1};
OS Candidatus Melainabacteria bacterium RIFOXYA2_FULL_32_9.
OC Bacteria; Candidatus Melainabacteria.
OX NCBI_TaxID=1801611 {ECO:0000313|EMBL:OGI21741.1, ECO:0000313|Proteomes:UP000198209};
RN [1] {ECO:0000313|EMBL:OGI21741.1, ECO:0000313|Proteomes:UP000198209}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=27774985; DOI=10.1038/ncomms13219;
RA Anantharaman K., Brown C.T., Hug L.A., Sharon I., Castelle C.J.,
RA Probst A.J., Thomas B.C., Singh A., Wilkins M.J., Karaoz U., Brodie E.L.,
RA Williams K.H., Hubbard S.S., Banfield J.F.;
RT "Thousands of microbial genomes shed light on interconnected biogeochemical
RT processes in an aquifer system.";
RL Nat. Commun. 7:13219-13219(2016).
CC -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
CC -!- SIMILARITY: Belongs to the HisA/HisF family.
CC {ECO:0000256|ARBA:ARBA00009667, ECO:0000256|RuleBase:RU003657}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OGI21741.1}.
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DR EMBL; MFRQ01000054; OGI21741.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1F6RM62; -.
DR STRING; 1801611.A2255_07405; -.
DR Proteomes; UP000198209; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR006062; His_biosynth.
DR InterPro; IPR011060; RibuloseP-bd_barrel.
DR PANTHER; PTHR21235:SF2; IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE HISHF; 1.
DR PANTHER; PTHR21235; IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE SUBUNIT HISF/H IGP SYNTHASE SUBUNIT HISF/H; 1.
DR Pfam; PF00977; His_biosynth; 1.
DR SUPFAM; SSF51366; Ribulose-phoshate binding barrel; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605,
KW ECO:0000256|RuleBase:RU003657};
KW Histidine biosynthesis {ECO:0000256|ARBA:ARBA00023102,
KW ECO:0000256|RuleBase:RU003657}.
SQ SEQUENCE 250 AA; 28131 MW; F21C2CED058CEBB1 CRC64;
MEVIGAINLY NGQCIDSLEP DHNVIEDCKP ISLAIKWNNI GVNWIHLVDV NGFREDNPIN
IDMIKDIISK VHVPIQVAAG IQDIESFEDI LAVGAGRIVL DNKALKNTDF IKKVLNEYPE
KTVVLLNVAS GMTKINGDYH ENASDIAKNL KNQGLERIIY RDISENYEFN YDDLIALAKN
VELPTIACGK LNDLGSIKKL KQMSDCEKVN IEGLILSKPL YDNTLDLYEV IKLIDAYPYI
GDFYSREDIC
//
